| 89BIO INC | COM | $67.7M | 2.2% | 9,316,333 SH | |
| ABIVAX SA | SPONSORED ADS | $22.4M | 0.7% | 3,579,209 SH | |
| AKERO THERAPEUTICS INC | COM | $130.0M | 4.2% | 3,210,270 SH | |
| ALIGOS THERAPEUTICS INC | COM NEW | $3.7M | 0.1% | 444,110 SH | |
| ALLAKOS INC | COM | $1.6M | 0.1% | 7,232,701 SH | |
| AMGEN INC | COM | $35.2M | 1.1% | 113,035 SH | |
| ANI PHARMACEUTICALS INC | COM | $46.9M | 1.5% | 700,000 SH | |
| APELLIS PHARMACEUTICALS INC | COM | $109.3M | 3.5% | 5,000,000 SH | |
| AUTOLUS THERAPEUTICS PLC | SPON ADS | $27.7M | 0.9% | 17,849,482 SH | |
| AVALO THERAPEUTICS INC | COM NEW | $6.9M | 0.2% | 859,876 SH | |
| BEAM THERAPEUTICS INC | COM | $6.2M | 0.2% | 315,765 SH | |
| BICARA THERAPEUTICS INC | COM | $26.1M | 0.8% | 2,000,000 SH | |
| BICYCLE THERAPEUTICS PLC | SPONSORED ADS | $6.5M | 0.2% | 767,016 SH | |
| BRIDGEBIO PHARMA INC | COM | $96.8M | 3.1% | 2,800,000 SH | |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | $36.3M | 1.2% | 2,000,000 SH | |
| CLIMB BIO INC | COM | $1.3M | 0.0% | 1,040,115 SH | |
| COMPASS PATHWAYS PLC | SPONSORED ADS | $25.3M | 0.8% | 8,859,648 SH | |
| CONTEXT THERAPEUTICS INC | COM | $4.5M | 0.1% | 7,419,355 SH | |
| CYBIN INC | COM NEW | $9.7M | 0.3% | 1,529,987 SH | |
| CYTOKINETICS INC | COM NEW | $123.5M | 4.0% | 3,073,853 SH | |
| DIANTHUS THERAPEUTICS INC | COM | $42.8M | 1.4% | 2,357,702 SH | |
| DYNAVAX TECHNOLOGIES CORP | COM NEW | $230.8M | 7.5% | 17,791,486 SH | |
| DYNE THERAPEUTICS INC | COM | $20.9M | 0.7% | 2,000,000 SH | |
| EDGEWISE THERAPEUTICS INC | COM | $30.8M | 1.0% | 1,400,000 SH | |
| ENGENE HOLDINGS INC | COM | $20.4M | 0.7% | 4,557,575 SH | |
| GALAPAGOS NV | SPON ADR | $18.6M | 0.6% | 741,068 SH | |
| GERON CORP | COM | $60.7M | 2.0% | 38,176,251 SH | |
| GH RESEARCH PLC | ORDINARY SHARES | $22.1M | 0.7% | 2,000,000 SH | |
| GUARDANT HEALTH INC | COM | $231.9M | 7.5% | 5,443,721 SH | |
| IKENA ONCOLOGY INC | COM | $3.2M | 0.1% | 2,515,513 SH | |
| IMMUNOCORE HLDGS PLC | ADS | $41.9M | 1.4% | 1,411,402 SH | |
| IMMUNOVANT INC | COM | $162.4M | 5.3% | 9,500,000 SH | |
| INOVIO PHARMACEUTICALS INC | COM SHS | $5.1M | 0.2% | 3,119,162 SH | |
| INSMED INC | COM PAR $.01 | $19.4M | 0.6% | 254,751 SH | |
| INTRA-CELLULAR THERAPIES INC | COM | $263.8M | 8.5% | 2,000,000 SH | |
| INVIVYD INC | COM | $5.9M | 0.2% | 9,722,254 SH | |
| IONIS PHARMACEUTICALS INC | COM | $137.7M | 4.5% | 4,564,207 SH | |
| KORRO BIO INC | COM | $15.2M | 0.5% | 874,614 SH | |
| MAZE THERAPEUTICS INC | COM | $36.0M | 1.2% | 3,269,126 SH | |
| MBX BIOSCIENCES INC | COM | $22.3M | 0.7% | 3,018,935 SH | |
| METSERA INC | COM | $29.8M | 1.0% | 1,094,408 SH | |
| MIND MEDICINE MINDMED INC | COM NEW | $14.6M | 0.5% | 2,500,000 SH | |
| NEUROGENE INC | COM | $1.4M | 0.0% | 116,660 SH | |
| NOVAVAX INC | COM NEW | $9.7M | 0.3% | 1,518,182 SH | |
| NURIX THERAPEUTICS INC | COM | $65.3M | 2.1% | 5,500,000 SH | |
| OCULAR THERAPEUTIX INC | COM | $104.8M | 3.4% | 14,294,420 SH | |
| OLEMA PHARMACEUTICALS INC | COM | $12.9M | 0.4% | 3,442,833 SH | |
| ONKURE THERAPEUTICS INC | COM CL A | $2.3M | 0.1% | 523,989 SH | |
| ORUKA THERAPEUTICS INC | COM | $14.8M | 0.5% | 1,444,709 SH | |
| PLIANT THERAPEUTICS INC | COM | $7.3M | 0.2% | 5,399,681 SH | |
| PROTAGONIST THERAPEUTICS INC | COM | $145.1M | 4.7% | 3,000,000 SH | |
| RAPPORT THERAPEUTICS INC | COM | $4.6M | 0.1% | 457,556 SH | |
| RAPT THERAPEUTICS INC | COM | $7.3M | 0.2% | 6,011,380 SH | |
| REGULUS THERAPEUTICS INC | COM | $5.7M | 0.2% | 3,262,564 SH | |
| SAGE THERAPEUTICS INC | COM | $16.2M | 0.5% | 2,038,845 SH | |
| SAREPTA THERAPEUTICS INC | COM | $57.4M | 1.9% | 899,731 SH | |
| SEPTERNA INC | COM | $11.1M | 0.4% | 1,912,929 SH | |
| SPYRE THERAPEUTICS INC | COM NEW | $3.5M | 0.1% | 219,015 SH | |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | $71.0M | 2.3% | 4,100,000 SH | |
| TARSUS PHARMACEUTICALS INC | COM | $76.2M | 2.5% | 1,484,266 SH | |
| TECTONIC THERAPEUTIC INC | COM | $24.8M | 0.8% | 1,401,938 SH | |
| TERNS PHARMACEUTICALS INC | COM | $15.4M | 0.5% | 5,576,558 SH | |
| ULTRAGENYX PHARMACEUTICAL IN | COM | $48.9M | 1.6% | 1,350,000 SH | |
| UPSTREAM BIO INC | COM | $14.1M | 0.5% | 2,299,567 SH | |
| VAXCYTE INC | COM | $28.3M | 0.9% | 750,000 SH | |
| VIRIDIAN THERAPEUTICS INC | COM | $72.5M | 2.3% | 5,380,449 SH | |
| XENCOR INC | COM | $5.8M | 0.2% | 549,439 SH | |
| XENON PHARMACEUTICALS INC | COM | $33.5M | 1.1% | 1,000,000 SH | |
| ZURA BIO LTD | CLASS A ORD SHS | $4.2M | 0.1% | 3,283,783 SH | |