| ABIVAX SA | SPONSORED ADS | $8.6M | 5.4% | 77,000 SH | New |
| ANTERIS TECHNOLOGIES GLOBAL | COM | $3.9M | 2.4% | 700,000 SH | New |
| ARROWHEAD PHARMACEUTICALS IN | COM | $408K | 0.3% | 6,500 SH | New |
| ARTIVA BIOTHERAPEUTICS INC | COM | $161K | 0.1% | 25,000 SH | New |
| AVALO THERAPEUTICS INC | COM NEW | $2.8M | 1.7%Prev: 0.9% | 185,122 SH | Increased+73,150 SH |
| CONTEXT THERAPEUTICS INC | COM | $262K | 0.2%Prev: 0.1% | 100,000 SH | Increased+10,000 SH |
| CORBUS PHARMACEUTICALS HLDGS | COM NEW | $244K | 0.2%Prev: 0.3% | 26,000 SH | Decreased-33,000 SH |
| CYTOMX THERAPEUTICS INC. | COM | $2.5M | 1.6% | 540,000 SH | New |
| DESIGN THERAPEUTICS INC | COM | $213K | 0.1%Prev: 0.1% | 20,000 SH | Increased+6,000 SH |
| EDESA BIOTECH INC | COM NEW | $4.3M | 2.7%Prev: 1.7% | 827,500 SH | Increased+140,000 SH |
| ESPERION THERAPEUTICS INC NE | COM | $4.7M | 3.0% | 1,720,000 SH | New |
| EUPRAXIA PHARMACEUTICALS INC | COM | $2.5M | 1.6% | 352,000 SH | New |
| EVOMMUNE INC | COM SHS | $10.3M | 6.4% | 446,255 SH | New |
| GOSSAMER BIO INC | COM | $23K | 0.0%Prev: 0.1% | 70,000 SH | Decreased-5,000 SH |
| HERON THERAPEUTICS INC | COM | $7.0M | 4.4%Prev: 15.8% | 8,753,290 SH | Decreased+1,766,546 SH |
| IMMIX BIOPHARMA INC | COM | $6.7M | 4.2% | 740,000 SH | New |
| IMMUNOME INC | COM | $219K | 0.1%Prev: 1.1% | 10,000 SH | Decreased-143,500 SH |
| INSPIREMD INC | COM | $3.4M | 2.1%Prev: 2.5% | 2,099,652 SH | Increased+1,195,623 SH |
| JASPER THERAPEUTICS INC | COM NEW | $2.3M | 1.5%Prev: 6.3% | 2,668,395 SH | Decreased+1,234,567 SH |
| KALARIS THERAPEUTICS INC | COM | $104K | 0.1% | 18,000 SH | New |
| KARYOPHARM THERAPEUTICS INC | COM NEW | $84K | 0.1% | 15,000 SH | New |
| KAZIA THERAPEUTICS LTD | SPONSORED ADS | $1.0M | 0.6% | 135,315 SH | New |
| LARIMAR THERAPEUTICS INC | COM | $149K | 0.1%Prev: 0.1% | 33,000 SH | Increased+5,000 SH |
| LYELL IMMUNOPHARMA INC | COM NEW | $2.0M | 1.3% | 102,000 SH | New |
| MACROGENICS INC | COM | $87K | 0.1% | 30,000 SH | New |
| MAPLIGHT THERAPEUTICS INC | COM | $10.0M | 6.3% | 492,893 SH | New |
| MINERALYS THERAPEUTICS INC | COM | $298K | 0.2%Prev: 2.5% | 11,000 SH | Decreased-139,600 SH |
| NASUS PHARMA LTD | ORD SHS | $798K | 0.5% | 359,390 SH | New |
| NEUMORA THERAPEUTICS INC. | COM | $156K | 0.1% | 80,000 SH | New |
| NURIX THERAPEUTICS INC | COM | $248K | 0.2% | 16,000 SH | New |
| OVID THERAPEUTICS INC | COM | $355K | 0.2%Prev: 0.0% | 160,000 SH | Increased+63,000 SH |
| PMV PHARMACEUTICALS INC | COM | $91K | 0.1%Prev: 0.0% | 73,000 SH | Increased+38,000 SH |
| PRAXIS PRECISION MEDICINES I | COM NEW | $32.5M | 20.3%Prev: 7.2% | 100,781 SH | Increased-84,219 SH |
| PRECISION BIOSCIENCES INC | COM NEW | $220K | 0.1% | 40,000 SH | New |
| PROFOUND MED CORP | COM NEW | $1.9M | 1.2% | 285,710 SH | New |
| PROQR THRAPEUTICS N V | SHS EURO | $73K | 0.0%Prev: 0.1% | 45,000 SH | Increased |
| PROTAGONIST THERAPEUTICS INC | COM | $390K | 0.2% | 3,700 SH | New |
| PROTARA THERAPEUTICS INC | COM STK | $14.8M | 9.3%Prev: 7.3% | 2,834,652 SH | Increased+1,166,852 SH |
| QUOIN PHARMACEUTICALS LTD | SPONSORED ADS | $560K | 0.4% | 84,849 SH | New |
| REPLIMUNE GROUP INC | COM | $153K | 0.1%Prev: 1.8% | 20,000 SH | Decreased-162,083 SH |
| REZOLUTE INC | COM NEW | $2.3M | 1.4%Prev: 1.2% | 750,000 SH | Increased+350,000 SH |
| ROCKET PHARMACEUTICALS INC | COM | $1.1M | 0.7% | 294,643 SH | New |
| SUTRO BIOPHARMA INC | COM SHS | $12.8M | 8.0% | 512,160 SH | New |
| SYNDAX PHARMACEUTICALS INC | COM | $234K | 0.1% | 10,000 SH | New |
| TENAX THERAPEUTICS INC | COM NEW | $9.3M | 5.8%Prev: 0.6% | 583,333 SH | Increased+500,000 SH |
| VERRICA PHARMACEUTICALS INC | COM SHS | $2.5M | 1.6% | 471,559 SH | New |
| VIRIDIAN THERAPEUTICS INC | COM | $1.8M | 1.1% | 91,123 SH | New |
| XENCOR INC | COM | $3.0M | 1.9% | 250,000 SH | New |
| XILIO THERAPEUTICS INC | COM | $120K | 0.1% | 14,285 SH | New |