| ALKERMES PLC | SHS | $243K | 0.2%Prev: 0.2% | 6,000 SH | Decreased |
| ARCUTIS BIOTHERAPEUTICS INC | COM | $264K | 0.2%Prev: 0.3% | 10,000 SH | Decreased-9,700 SH |
| ARDELYX INC | COM | $103K | 0.1%Prev: 0.2% | 30,000 SH | Decreased-30,000 SH |
| ARGENX SE | SPONSORED ADR | $288K | 0.2%Prev: 0.3% | 300 SH | Decreased-341 SH |
| ASCENDIS PHARMA A/S | ORD SHS | $228K | 0.2%Prev: 0.2% | 1,000 SH | Decreased-500 SH |
| AURINIA PHARMACEUTICALS INC | COM | $243K | 0.2%Prev: 0.3% | 15,000 SH | Decreased-15,000 SH |
| COMPASS PATHWAYS PLC | SPONSORED ADS | $124K | 0.1%Prev: 0.1% | 10,000 SH | Decreased-8,000 SH |
| CYTOMX THERAPEUTICS INC. | COM | $107K | 0.1%Prev: 0.1% | 39,400 SH | Decreased |
| DEFINIUM THERAPEUTICS INC | COM SHS | $247K | 0.2%Prev: 0.3% | 6,500 SH | Decreased-3,500 SH |
| DIANTHUS THERAPEUTICS INC | COM | $220K | 0.2%Prev: 0.1% | 2,500 SH | Decreased |
| DYNE THERAPEUTICS INC | COM | $161K | 0.1%Prev: 0.2% | 10,000 SH | Decreased-10,000 SH |
| EDGEWISE THERAPEUTICS INC | COM | $203K | 0.1%Prev: 0.1% | 5,000 SH | Decreased |
| EXELIXIS INC | COM | $292K | 0.2%Prev: 0.2% | 5,000 SH | Decreased-3,000 SH |
| HALOZYME THERAPEUTICS INC | COM | $331K | 0.2%Prev: 0.3% | 3,000 SH | Decreased-4,000 SH |
| HARMONY BIOSCIENCES HLDGS IN | COM | $275K | 0.2%Prev: 0.2% | 7,000 SH | Decreased-3,000 SH |
| IMMUNOCORE HLDGS PLC | ADS | $212K | 0.1%Prev: 0.3% | 7,000 SH | Decreased-8,141 SH |
| IMMUNOME INC | COM | $258K | 0.2%Prev: 0.2% | 12,000 SH | Decreased-6,000 SH |
| IMMUNOVANT INC | COM | $236K | 0.2%Prev: 0.3% | 7,000 SH | Decreased-6,000 SH |
| INCYTE CORP | COM | $243K | 0.2%Prev: 0.3% | 2,000 SH | Decreased-3,300 SH |
| INTELLIA THERAPEUTICS INC | COM | $241K | 0.2%Prev: 0.2% | 20,000 SH | Decreased |
| ISHARES TR | 0-3 MTH TREASURY | $70.5M | 48.3%Prev: 37.5% | 700,000 SH | Increased |
| KINIKSA PHARMACEUTICALS INTL | ORD SHS CL A | $261K | 0.2%Prev: 0.2% | 3,500 SH | Decreased-1,500 SH |
| KRYSTAL BIOTECH INC | COM | $230K | 0.2%Prev: 0.1% | 692 SH | Decreased |
| KYMERA THERAPEUTICS INC | COM | $224K | 0.2%Prev: 0.2% | 2,000 SH | Decreased-2,000 SH |
| MADRIGAL PHARMACEUTICALS INC | COM | $302K | 0.2%Prev: 0.2% | 600 SH | Decreased |
| MIRUM PHARMACEUTICALS INC | COM | $214K | 0.1%Prev: 0.2% | 2,500 SH | Decreased |
| NEUROCRINE BIOSCIENCES INC | COM | $255K | 0.2%Prev: 0.3% | 1,800 SH | Decreased-1,200 SH |
| NURIX THERAPEUTICS INC | COM | $285K | 0.2%Prev: 0.3% | 12,000 SH | Decreased-13,000 SH |
| OCULAR THERAPEUTIX INC | COM | $115K | 0.1%Prev: 0.1% | 15,000 SH | Decreased |
| OLEMA PHARMACEUTICALS INC | COM | $86K | 0.1%Prev: 0.1% | 10,000 SH | Decreased |
| ORIC PHARMACEUTICALS INC | COM | $175K | 0.1%Prev: 0.1% | 13,000 SH | Increased |
| ORUKA THERAPEUTICS INC | COM | $250K | 0.2%Prev: 0.2% | 3,000 SH | Decreased |
| PROTAGONIST THERAPEUTICS INC | COM | $211K | 0.1%Prev: 0.2% | 1,500 SH | Decreased-1,500 SH |
| REVOLUTION MEDICINES INC | COM | $246K | 0.2%Prev: 0.1% | 1,200 SH | Increased |
| ROYALTY PHARMA PLC | SHS CLASS A | $292K | 0.2%Prev: 0.3% | 5,000 SH | Decreased-6,000 SH |
| SERA PROGNOSTICS INC | CLASS A COM | $5.0M | 3.4% | 2,396,685 SH | New |
| SPDR SERIES TRUST | ST STR SP BIOT | $60.9M | 41.8%Prev: 48.0% | 386,500 SH | Decreased-183,500 SH |
| STOKE THERAPEUTICS INC | COM | $234K | 0.2%Prev: 0.2% | 9,000 SH | Decreased-3,000 SH |
| SUPERNUS PHARMACEUTICALS | COM | $258K | 0.2%Prev: 0.1% | 6,000 SH | Decreased |
| SYNDAX PHARMACEUTICALS INC | COM | $226K | 0.2%Prev: 0.2% | 12,000 SH | Decreased-8,000 SH |
| TANGO THERAPEUTICS INC | COM | $250K | 0.2%Prev: 0.2% | 10,000 SH | Decreased |
| TARSUS PHARMACEUTICALS INC | COM | $275K | 0.2%Prev: 0.2% | 3,500 SH | Decreased-3,500 SH |
| TG THERAPEUTICS INC | COM | $279K | 0.2%Prev: 0.3% | 5,000 SH | Decreased-5,000 SH |
| TREVI THERAPEUTICS INC | COM | $215K | 0.1%Prev: 0.3% | 15,000 SH | Decreased-15,000 SH |