| ABIVAX SA | SPONSORED ADS | $5.3M | 1.1% | 47,193 SH | New |
| ADAPTIVE BIOTECHNOLOGIES COR | COM | $10.0M | 2.1%Prev: 1.1% | 722,784 SH | Increased+111,145 SH |
| ASCENDIS PHARMA A/S | SPONSORED ADR | $29.5M | 6.2%Prev: 7.4% | 129,111 SH | Decreased-66,412 SH |
| ATAIBECKLEY INC | COM SHS | $697K | 0.1% | 196,858 SH | New |
| BOSTON SCIENTIFIC CORP | COM | $18.8M | 3.9% | 299,318 SH | New |
| BRIDGEBIO PHARMA INC | COM | $32.1M | 6.7%Prev: 8.1% | 432,014 SH | Decreased-530,869 SH |
| BRISTOL-MYERS SQUIBB CO | COM | $25.5M | 5.3% | 420,727 SH | New |
| CORVUS PHARMACEUTICALS INC | COM | $13.0M | 2.7% | 891,933 SH | New |
| CYTOKINETICS INC | COM NEW | $14.2M | 3.0%Prev: 5.7% | 215,501 SH | Decreased-370,311 SH |
| DEFINIUM THERAPEUTICS INC | COM SHS | $19.6M | 4.1% | 1,037,984 SH | New |
| DIANTHUS THERAPEUTICS INC | COM | $47.0M | 9.8%Prev: 3.4% | 560,308 SH | Increased-203,163 SH |
| DISC MEDICINE INC | COM | $7.9M | 1.6% | 122,978 SH | New |
| DYNE THERAPEUTICS INC | COM | $5.1M | 1.1% | 282,954 SH | New |
| EDWARDS LIFESCIENCES CORP | COM | $11.6M | 2.4%Prev: 7.7% | 144,607 SH | Decreased-290,981 SH |
| ELEDON PHARMACEUTICALS INC | COM | $5.1M | 1.1% | 1,639,816 SH | New |
| FRACTYL HEALTH INC | COM | $2.5M | 0.5%Prev: 0.1% | 5,491,866 SH | Increased+5,277,630 SH |
| GILEAD SCIENCES INC | COM | $22.8M | 4.8% | 163,905 SH | New |
| HEARTFLOW INC | COM | $9.8M | 2.1% | 403,588 SH | New |
| HYPERFINE INC | COM CL A | $1.4M | 0.3%Prev: 0.1% | 1,320,041 SH | Increased+560,006 SH |
| IMMUNOCORE HLDGS PLC | ADS | $2.5M | 0.5% | 84,352 SH | New |
| INCYTE CORP | COM | $17.1M | 3.6% | 182,101 SH | New |
| KALVISTA PHARMACEUTICALS INC | COM | $8.6M | 1.8% | 426,551 SH | New |
| KARYOPHARM THERAPEUTICS INC | COM NEW | $5.0M | 1.0%Prev: 0.1% | 897,709 SH | Increased+742,087 SH |
| METAGENOMI THERAPEUTICS INC | COM | $709K | 0.1% | 528,993 SH | New |
| MINERALYS THERAPEUTICS INC | COM | $11.9M | 2.5% | 439,041 SH | New |
| NATERA INC | COM | $14.2M | 3.0% | 70,907 SH | New |
| NEWAMSTERDAM PHARMA COMPANY | ORDINARY SHARES | $2.7M | 0.6% | 83,554 SH | New |
| OUTSET MED INC | COM NEW | $454K | 0.1%Prev: 0.4% | 118,279 SH | Decreased-48,387 SH |
| PHATHOM PHARMACEUTICALS INC | COM | $2.8M | 0.6% | 247,767 SH | New |
| PROTARA THERAPEUTICS INC | COM STK | $3.0M | 0.6%Prev: 1.1% | 580,024 SH | Decreased-508,667 SH |
| SENSEI BIOTHERAPEUTICS INC | COM NEW | $464K | 0.1% | 14,718 SH | New |
| SEPTERNA INC | COM | $7.1M | 1.5%Prev: 1.4% | 294,360 SH | Increased-729,885 SH |
| SOLENO THERAPEUTICS INC | COM | $19.3M | 4.0%Prev: 2.8% | 577,808 SH | Increased+416,846 SH |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | $12.3M | 2.6%Prev: 3.0% | 255,379 SH | Increased-449,485 SH |
| SUPERNUS PHARMACEUTICALS | COM | $3.2M | 0.7% | 62,019 SH | New |
| SYNDAX PHARMACEUTICALS INC | COM | $24.4M | 5.1%Prev: 5.2% | 1,043,670 SH | Increased-690,031 SH |
| TERNS PHARMACEUTICALS INC | COM | $21.6M | 4.5% | 409,031 SH | New |
| TYRA BIOSCIENCES INC | COM | $2.6M | 0.5% | 67,285 SH | New |
| ULTRAGENYX PHARMACEUTICAL IN | COM | $17.8M | 3.7% | 850,797 SH | New |
| UNIQURE NV | SHS | $8.0M | 1.7%Prev: 2.1% | 491,116 SH | Decreased-339,209 SH |
| VERADERMICS INC | COMMON STOCK | $11.0M | 2.3% | 173,582 SH | New |