| Abbott Laboratories | COM | $75.2M | 2.6%Prev: 1.5% | 600,000 SH | Increased+350,000 SH |
| Abivax SA | SPONSORED ADS | $256.2M | 8.7%Prev: 3.8% | 1,900,000 SH | Increased+900,000 SH |
| Agios Pharmaceuticals Inc | COM | $8.8M | 0.3%Prev: 0.2% | 325,000 SH | Increased+198,000 SH |
| Alcon AG | ORD SHS | $87.1M | 3.0%Prev: 3.7% | 1,105,000 SH | Increased+5,000 SH |
| Alector Inc | COM | $1.2M | 0.0%Prev: 0.1% | 755,000 SH | Decreased-225,000 SH |
| Alto Neuroscience Inc | COM SHS | $44.2M | 1.5%Prev: 0.2% | 2,485,000 SH | Increased+1,535,000 SH |
| Apogee Therapeutics Inc | COM | $41.5M | 1.4%Prev: 0.8% | 550,000 SH | Increased+125,000 SH |
| Arcellx Inc | COMMON STOCK | $190.7M | 6.5%Prev: 4.6% | 2,925,000 SH | Increased+1,675,000 SH |
| Arrowhead Pharmaceuticals Inc | COM | $59.8M | 2.0% | 900,000 SH | New |
| Ascendis Pharma A/S | SPONSORED ADR | $37.3M | 1.3%Prev: 5.4% | 175,000 SH | Decreased-425,000 SH |
| Axsome Therapeutics Inc | COM | $38.4M | 1.3%Prev: 0.8% | 210,000 SH | Increased+60,000 SH |
| Beta Bionics Inc | COM | $18.3M | 0.6%Prev: 0.5% | 600,000 SH | Increased |
| Bicara Therapeutics Inc | COM | $60.2M | 2.0%Prev: 3.6% | 3,575,000 SH | Decreased-1,525,000 SH |
| BioCryst Pharmaceuticals Inc | COM | $17.6M | 0.6% | 2,250,000 SH | New |
| BioMarin Pharmaceutical Inc | COM | $178.3M | 6.1%Prev: 2.0% | 3,000,000 SH | Increased+2,170,000 SH |
| Black Diamond Therapeutics Inc | COM | $2.1M | 0.1%Prev: 0.9% | 870,000 SH | Decreased-4,680,000 SH |
| Bristol-Myers Squibb Co | COM | $13.5M | 0.5% | 250,000 SH | New |
| Celldex Therapeutics Inc | COM NEW | $31.6M | 1.1%Prev: 1.4% | 1,165,000 SH | Increased-40,000 SH |
| Crescent Biopharma Inc | COM | $17.8M | 0.6% | 1,500,000 SH | New |
| Day One Biopharmaceuticals Inc | COM | $48.5M | 1.6%Prev: 0.9% | 5,200,000 SH | Increased+2,525,000 SH |
| DBV Technologies SA | SPONSORED ADS | $5.8M | 0.2% | 300,000 SH | New |
| Definium Therapeutics Inc | COM NEW | $8.5M | 0.3% | 637,000 SH | New |
| Denali Therapeutics Inc | COM | $7.7M | 0.3% | 465,000 SH | New |
| Dexcom Inc | COM | $84.6M | 2.9%Prev: 2.0% | 1,275,000 SH | Increased+625,000 SH |
| Disc Medicine Inc | COM | $58.4M | 2.0%Prev: 1.5% | 735,000 SH | Increased+235,000 SH |
| Dyne Therapeutics Inc | COM | $2.3M | 0.1%Prev: 1.6% | 120,000 SH | Decreased-2,655,000 SH |
| Engene Holdings Inc | COM | $9.5M | 0.3%Prev: 0.1% | 1,055,000 SH | Increased+685,000 SH |
| Enliven Therapeutics Inc | COM | $59.0M | 2.0%Prev: 1.1% | 3,830,000 SH | Increased+2,670,000 SH |
| Fate Therapeutics Inc | COM | $1.7M | 0.1%Prev: 0.1% | 1,725,000 SH | Decreased-790,000 SH |
| Fulcrum Therapeutics Inc | COM | $10.7M | 0.4% | 950,000 SH | New |
| Geron Corp | COM | $14.9M | 0.5%Prev: 1.1% | 11,320,000 SH | Decreased-5,905,000 SH |
| Gilead Sciences Inc | COM | $6.1M | 0.2% | 50,000 SH | New |
| Globus Medical Inc | CL A | $111.3M | 3.8%Prev: 3.2% | 1,275,000 SH | Increased+25,000 SH |
| Immatics NV | SHS | $64.3M | 2.2%Prev: 2.4% | 6,125,000 SH | Increased-225,000 SH |
| Immunocore Holdings PLC | ADS | $20.3M | 0.7% | 585,000 SH | New |
| Invesco QQQ Trust Series 1 | UNIT SER 1 | $215.0M | 7.3% | 350,000 SH | New |
| Jazz Pharmaceuticals PLC | SHS USD | $49.3M | 1.7%Prev: 3.0% | 290,000 SH | Decreased-210,000 SH |
| KalVista Pharmaceuticals Inc | COM | $30.5M | 1.0%Prev: 0.4% | 1,890,000 SH | Increased+1,140,000 SH |
| Lantheus Holdings Inc | COM | $24.0M | 0.8%Prev: 0.4% | 360,000 SH | Increased+190,000 SH |
| LENZ Therapeutics Inc | COM | $4.4M | 0.1% | 275,000 SH | New |
| Lexeo Therapeutics Inc | COM | $44.4M | 1.5%Prev: 1.0% | 4,475,000 SH | Increased+1,225,000 SH |
| MacroGenics Inc | COM | $451K | 0.0%Prev: 0.0% | 280,000 SH | Decreased |
| MapLight Therapeutics Inc | COM | $6.8M | 0.2% | 385,000 SH | New |
| Merck & Co Inc | COM | $81.6M | 2.8% | 775,000 SH | New |
| Mirum Pharmaceuticals Inc | COM | $5.2M | 0.2% | 66,000 SH | New |
| Monte Rosa Therapeutics Inc | COM | $12.2M | 0.4%Prev: 0.3% | 775,000 SH | Increased-25,000 SH |
| Myriad Genetics Inc | COM | $7.5M | 0.3%Prev: 0.2% | 1,223,000 SH | Increased+623,000 SH |
| Novocure Ltd | ORD SHS | $6.8M | 0.2%Prev: 0.2% | 525,000 SH | Increased+125,000 SH |
| Nurix Therapeutics Inc | COM | $89.0M | 3.0%Prev: 1.4% | 4,690,000 SH | Increased+1,215,000 SH |
| Nuvalent Inc | COM | $4.6M | 0.2%Prev: 4.3% | 46,000 SH | Decreased-1,054,000 SH |
| Nyxoah SA | SHS | $5.1M | 0.2%Prev: 0.2% | 1,107,000 SH | Decreased-413 SH |
| Olema Pharmaceuticals Inc | COM | $41.3M | 1.4% | 1,650,000 SH | New |
| OnKure Therapeutics Inc | COM CL A | $1.8M | 0.1%Prev: 0.1% | 635,000 SH | Increased |
| Passage Bio Inc | COM NEW | $3.6M | 0.1%Prev: 0.1% | 305,000 SH | Increased |
| Penumbra Inc | COM | $15.5M | 0.5% | 50,000 SH | New |
| Rapport Therapeutics Inc | COM | $33.7M | 1.1%Prev: 1.3% | 1,110,000 SH | Increased+160,000 SH |
| REGENXBIO Inc | COM | $490K | 0.0% | 34,000 SH | New |
| Repligen Corp | COM | $13.6M | 0.5%Prev: 2.4% | 83,000 SH | Decreased-317,000 SH |
| Revolution Medicines Inc | COM | $23.5M | 0.8%Prev: 1.3% | 295,000 SH | Decreased-335,000 SH |
| Rezolute Inc | COM NEW | $4.0M | 0.1% | 1,686,000 SH | New |
| Savara Inc | COM | $9.7M | 0.3%Prev: 0.6% | 1,606,000 SH | Decreased-2,409,000 SH |
| Scholar Rock Holding Corp | COM | $30.8M | 1.0%Prev: 2.5% | 700,000 SH | Decreased-800,000 SH |
| Solid Biosciences Inc | COM NEW | $32.8M | 1.1%Prev: 0.8% | 5,815,000 SH | Increased+2,840,000 SH |
| Structure Therapeutics Inc | SPONSORED ADS | $2.4M | 0.1% | 35,000 SH | New |
| Sutro Biopharma Inc | COM SHS | $2.8M | 0.1% | 243,000 SH | New |
| Taysha Gene Therapies Inc | COM SHS | $75.6M | 2.6%Prev: 0.8% | 13,750,000 SH | Increased+8,250,000 SH |
| Tectonic Therapeutic Inc | COM | $6.8M | 0.2% | 328,000 SH | New |
| Tenax Therapeutics Inc | COM NEW | $651K | 0.0%Prev: 0.0% | 53,439 SH | Increased |
| Terns Pharmaceuticals Inc | COM | $181.8M | 6.2% | 4,500,000 SH | New |
| Tyra Biosciences Inc | COM | $63.8M | 2.2%Prev: 1.5% | 2,425,000 SH | Increased |
| Upstream Bio Inc | COM | $19.5M | 0.7% | 720,000 SH | New |
| Vera Therapeutics Inc | CL A | $27.9M | 0.9%Prev: 1.0% | 550,000 SH | Increased-210,000 SH |
| Voyager Therapeutics Inc | COM | $5.8M | 0.2%Prev: 0.3% | 1,475,000 SH | Decreased |
| Xenon Pharmaceuticals Inc | COM | $26.9M | 0.9%Prev: 2.0% | 600,000 SH | Decreased-500,000 SH |
| Zimmer Biomet Holdings Inc | COM | $13.5M | 0.5% | 150,000 SH | New |
| Zymeworks Inc | COM | $22.8M | 0.8%Prev: 1.4% | 865,000 SH | Decreased-900,000 SH |