| ABBVIE INC | COM | $5.8M | 1.1%Prev: 1.0% | 25,256 SH | Decreased-5,000 SH |
| ACADIA PHARMACEUTICALS INC | COM | $5.7M | 1.1%Prev: 1.2% | 212,202 SH | Decreased-144,332 SH |
| ADVANCED MICRO DEVICES INC | COM | $3.9M | 0.7% | 18,040 SH | New |
| ALPHA COGNITION INC | COM NEW | $3.7M | 0.7%Prev: 0.5% | 567,616 SH | Decreased+21,800 SH |
| AMGEN INC | COM | $2.5M | 0.5%Prev: 0.4% | 7,500 SH | Decreased |
| AMICUS THERAPEUTICS INC | COM | $9.4M | 1.8% | 658,377 SH | New |
| ANNEXON INC | COM | $6.6M | 1.3% | 1,316,212 SH | New |
| APELLIS PHARMACEUTICALS INC | COM | $6.3M | 1.2% | 250,961 SH | New |
| APPLIED THERAPEUTICS INC | COM | $5K | 0.0% | 50,000 SH | New |
| APREA THERAPEUTICS INC | COM NEW | $230K | 0.0%Prev: 0.0% | 270,000 SH | Increased |
| ASCENDIS PHARMA A/S | SPONSORED ADR | $2.3M | 0.5% | 11,000 SH | New |
| ASTRAZENECA PLC | SPONSORED ADR | $12.4M | 2.4% | 135,060 SH | New |
| ASTRIA THERAPEUTICS INC | COM | $4.7M | 0.9% | 355,725 SH | New |
| BIOAGE LABS INC | COM | $3.2M | 0.6%Prev: 0.7% | 243,035 SH | Decreased+29,364 SH |
| BIOCRYST PHARMACEUTICALS INC | COM | $6.5M | 1.3%Prev: 0.6% | 837,889 SH | Increased+415,838 SH |
| BIOGEN INC | COM | $16.7M | 3.2%Prev: 5.5% | 94,738 SH | Decreased-101,888 SH |
| BIOMARIN PHARMACEUTICAL INC | COM | $8.7M | 1.7%Prev: 2.5% | 147,000 SH | Decreased-181,550 SH |
| BRIDGEBIO PHARMA INC | COM | $8.2M | 1.6%Prev: 2.4% | 107,746 SH | Decreased-137,600 SH |
| BRISTOL-MYERS SQUIBB CO | COM | $944K | 0.2% | 17,500 SH | New |
| BROADCOM INC | COM | $3.4M | 0.7% | 9,755 SH | New |
| CAMTEK LTD | ORD | $4.2M | 0.8% | 39,498 SH | New |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | $6.5M | 1.3%Prev: 1.2% | 239,764 SH | Decreased-1,104 SH |
| CLIMB BIO INC | COM | $3.7M | 0.7%Prev: 0.8% | 932,247 SH | Decreased+448,500 SH |
| COGENT BIOSCIENCES INC | COM | $13.4M | 2.6%Prev: 2.3% | 378,500 SH | Decreased-80,840 SH |
| CONTINEUM THERAPEUTICS INC | CL A | $2.0M | 0.4%Prev: 0.4% | 173,475 SH | Decreased-10,000 SH |
| CORVUS PHARMACEUTICALS INC | COM | $3.1M | 0.6%Prev: 0.5% | 407,709 SH | Decreased+162,748 SH |
| CYBIN INC | COM NEW | $6.8M | 1.3%Prev: 1.4% | 825,576 SH | Decreased-795,177 SH |
| CYTOKINETICS INC | COM NEW | $5.8M | 1.1%Prev: 3.6% | 91,717 SH | Decreased-228,270 SH |
| DAY ONE BIOPHARMACEUTICALS I | COM | $1.4M | 0.3% | 145,371 SH | New |
| DYNE THERAPEUTICS INC | COM | $7.7M | 1.5%Prev: 0.6% | 392,894 SH | Increased+193,300 SH |
| ELBIT SYS LTD | ORD | $3.1M | 0.6% | 5,340 SH | New |
| ELEDON PHARMACEUTICALS INC | COM | $3.2M | 0.6%Prev: 0.6% | 2,132,131 SH | Decreased+940,944 SH |
| ELI LILLY & CO | COM | $9.7M | 1.9%Prev: 1.3% | 9,040 SH | Increased+1,000 SH |
| ENLIVEN THERAPEUTICS INC | COM | $3.5M | 0.7%Prev: 0.7% | 226,765 SH | Decreased+114,000 SH |
| ENPHASE ENERGY INC | COM | $6.0M | 1.2% | 186,500 SH | New |
| ENTRADA THERAPEUTICS INC | COM | $1.1M | 0.2% | 110,942 SH | New |
| EVOMMUNE INC | COM SHS | $2.8M | 0.5%Prev: 0.0% | 166,147 SH | Increased+143,515 SH |
| FORTE BIOSCIENCES INC | COM NEW | $5.1M | 1.0%Prev: 0.7% | 185,869 SH | Decreased-63,824 SH |
| GSK PLC | SPONSORED ADR | $6.0M | 1.2%Prev: 0.7% | 122,000 SH | Increased+20,000 SH |
| IMMATICS N.V | SHS | $9.0M | 1.7%Prev: 1.0% | 861,105 SH | Increased+141,048 SH |
| ISHARES BITCOIN TRUST ETF | SHS BEN INT | $1.5M | 0.3% | 30,055 SH | New |
| ISHARES TR | 20 YR TR BD ETF | $4.1M | 0.8%Prev: 0.5% | 47,000 SH | Increased |
| JANUX THERAPEUTICS INC | COM | $2.2M | 0.4% | 157,840 SH | New |
| JASPER THERAPEUTICS INC | COM NEW | $888K | 0.2% | 485,401 SH | New |
| JOHNSON & JOHNSON | COM | $7.4M | 1.4%Prev: 1.0% | 35,831 SH | Increased+7,000 SH |
| KODIAK SCIENCES INC | COM | $4.9M | 0.9%Prev: 0.4% | 175,500 SH | Increased+93,704 SH |
| KURA ONCOLOGY INC | COM | $3.1M | 0.6%Prev: 0.4% | 295,522 SH | Decreased+483 SH |
| MADRIGAL PHARMACEUTICALS INC | COM | $1.9M | 0.4%Prev: 1.2% | 3,300 SH | Decreased-14,119 SH |
| MAZE THERAPEUTICS INC | COM | $3.0M | 0.6%Prev: 1.6% | 71,843 SH | Decreased-345,721 SH |
| MEDIWOUND LTD | SHS NEW | $4.3M | 0.8%Prev: 0.5% | 230,347 SH | Increased-42,845 SH |
| MERCK & CO INC | COM | $5.1M | 1.0%Prev: 1.0% | 48,600 SH | Decreased-10,000 SH |
| MEREO BIOPHARMA GROUP PLC | SPON ADS | $106K | 0.0% | 255,400 SH | New |
| MINERALYS THERAPEUTICS INC | COM | $16.3M | 3.1%Prev: 5.2% | 449,003 SH | Decreased-1,020,968 SH |
| NICE LTD | SPONSORED ADR | $6.3M | 1.2% | 55,700 SH | New |
| NOVA LTD | COM | $15.7M | 3.0%Prev: 1.8% | 47,846 SH | Increased+22,677 SH |
| NOVARTIS AG | SPONSORED ADR | $5.1M | 1.0%Prev: 1.0% | 37,000 SH | Decreased-13,000 SH |
| NOVO-NORDISK A S | ADR | $5.9M | 1.1%Prev: 0.8% | 115,677 SH | Increased-5,000 SH |
| NURIX THERAPEUTICS INC | COM | $2.4M | 0.5% | 124,000 SH | New |
| ONKURE THERAPEUTICS INC | COM CL A | $175K | 0.0% | 60,454 SH | New |
| ORIC PHARMACEUTICALS INC | COM | $8.2M | 1.6%Prev: 1.2% | 1,004,378 SH | Decreased+151,395 SH |
| PALISADE BIO INC | COM | $433K | 0.1%Prev: 0.6% | 184,100 SH | Decreased-2,073,006 SH |
| PEPGEN INC | COM | $791K | 0.2% | 121,467 SH | New |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | $962K | 0.2% | 349,973 SH | New |
| PFIZER INC | COM | $2.1M | 0.4%Prev: 0.9% | 86,000 SH | Decreased-200,000 SH |
| PHARVARIS N V | COM | $1.8M | 0.3% | 63,953 SH | New |
| PRAXIS PRECISION MEDICINES I | COM NEW | $11.8M | 2.3%Prev: 0.5% | 40,000 SH | Increased+27,500 SH |
| PRECISION BIOSCIENCES INC | COM NEW | $1.6M | 0.3% | 396,116 SH | New |
| PRELUDE THERAPEUTICS INC | COM | $356K | 0.1%Prev: 0.7% | 122,752 SH | Decreased-897,080 SH |
| PROMIS NEUROSCIENCES INC | COM SHS | $81K | 0.0%Prev: 0.6% | 11,807 SH | Decreased-313,784 SH |
| PROTARA THERAPEUTICS INC | COM STK | $3.5M | 0.7% | 650,000 SH | New |
| REVOLUTION MEDICINES INC | COM | $4.2M | 0.8%Prev: 0.5% | 52,500 SH | Decreased+30,100 SH |
| SANOFI SA | SPONSORED ADR | $11.6M | 2.2%Prev: 1.5% | 239,515 SH | Increased-30,000 SH |
| SAVARA INC | COM | $7.1M | 1.4%Prev: 0.6% | 1,178,164 SH | Increased+422,000 SH |
| SCHOLAR ROCK HLDG CORP | COM | $7.0M | 1.3%Prev: 0.7% | 158,265 SH | Increased+64,000 SH |
| SHATTUCK LABS INC | COM | $713K | 0.1%Prev: 0.1% | 195,212 SH | Increased+108,751 SH |
| SKYE BIOSCIENCE INC | COM NEW | $359K | 0.1%Prev: 0.1% | 478,928 SH | Decreased-200,000 SH |
| SOLAREDGE TECHNOLOGIES INC | COM | $5.7M | 1.1% | 196,536 SH | New |
| SOLAREDGE TECHNOLOGIES INC | NOTE 2.250% 7/0 | $4.7M | 0.9%Prev: 1.0% | 4,000,000 SH | Decreased |
| SOLENO THERAPEUTICS INC | COM | $6.3M | 1.2% | 136,314 SH | New |
| SPDR SERIES TRUST | STATE STREET SPD | $8.5M | 1.6% | 70,000 SH | New |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | $2.9M | 0.6%Prev: 0.2% | 41,000 SH | Increased+12,400 SH |
| SYNDAX PHARMACEUTICALS INC | COM | $16.0M | 3.1%Prev: 2.9% | 762,563 SH | Decreased-252,043 SH |
| TANGO THERAPEUTICS INC | COM | $4.8M | 0.9%Prev: 1.0% | 544,563 SH | Decreased+290,313 SH |
| TAYSHA GENE THERAPIES INC | COM SHS | $2.0M | 0.4%Prev: 0.2% | 368,146 SH | Increased+118,146 SH |
| TENAX THERAPEUTICS INC | COM NEW | $2.3M | 0.4%Prev: 0.5% | 190,111 SH | Decreased-57,689 SH |
| TENAYA THERAPEUTICS INC | COM | $1.1M | 0.2% | 1,500,000 SH | New |
| TEVA PHARMACEUTICAL INDS LTD | SPONSORED ADS | $35.1M | 6.8%Prev: 6.6% | 1,123,525 SH | Decreased-376,557 SH |
| TOWER SEMICONDUCTOR LTD | SHS NEW | $14.4M | 2.8%Prev: 3.7% | 122,513 SH | Decreased+14,248 SH |
| TREVI THERAPEUTICS INC | COM | $7.5M | 1.4%Prev: 1.2% | 598,534 SH | Decreased+99,505 SH |
| ULTRAGENYX PHARMACEUTICAL IN | COM | $15.0M | 2.9%Prev: 2.6% | 650,623 SH | Decreased+62,129 SH |
| VARONIS SYS INC | COM | $1.7M | 0.3% | 52,500 SH | New |
| VENTYX BIOSCIENCES INC | COM | $1.6M | 0.3% | 180,114 SH | New |
| VERASTEM INC | COM NEW | $2.7M | 0.5%Prev: 0.3% | 343,678 SH | Increased-288,954 SH |
| VOR BIOPHARMA INC | COM NEW | $5.4M | 1.0%Prev: 1.0% | 410,417 SH | Decreased-6,000 SH |
| VOYAGER THERAPEUTICS INC | COM | $1.3M | 0.3%Prev: 0.2% | 339,761 SH | Decreased-87,793 SH |
| WAVE LIFE SCIENCES LTD | SHS | $6.9M | 1.3%Prev: 0.5% | 408,166 SH | Increased-230,106 SH |
| WEREWOLF THERAPEUTICS INC | COM | $397K | 0.1%Prev: 0.0% | 626,810 SH | Increased |
| ZIM INTEGRATED SHIPPING SERV | SHS | $2.9M | 0.6% | 136,005 SH | New |