Rock Springs Capital Management LP

CIK 0001595725 • 6 13F filings • May 15, 2025 – Aug 14, 2026

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Filer information

Filed by: Rock Springs Capital Management LP, Chief Financial Officer
Address: 650 South Exeter Street, Suite 1070, Baltimore, MD, 21202
Phone: 410-220-0129
AUM: $1.95B

AUM over time

$2.05B latest

Sector allocation over time

Past 5 quarters

Q4 2025

Q3 2025

Q2 2026

Q2 2025

Q1 2026

HealthcareOther

Holdings by filing

Portfolio value: $1.95B98 positionsView on SEC.gov

			% of Portfolio
ACADIA HEALTHCARE COMPANY IN	COM	$1.7M	0.1%Prev: 0.2%	120,000 SH	Decreased-50,000 SH
ACLARIS THERAPEUTICS INC	COM	$13.4M	0.7%Prev: 0.5%	4,453,741 SH	Increased-155,568 SH
AGILON HEALTH INC	COM	$4.5M	0.2%Prev: 0.4%	6,500,000 SH	Decreased-466,300 SH
AGIOS PHARMACEUTICALS INC	COM	$21.8M	1.1%Prev: 2.2%	799,163 SH	Decreased-159,379 SH
ALKERMES PLC	SHS	$3.9M	0.2%Prev: 0.2%	139,228 SH	Increased+32,691 SH
ALNYLAM PHARMACEUTICALS INC	COM	$28.3M	1.5%Prev: 2.0%	71,250 SH	Decreased-3,000 SH
ALPHATEC HLDGS INC	COM NEW	$6.4M	0.3%Prev: 0.3%	302,500 SH	Increased
AMICUS THERAPEUTICS INC	COM	$27.5M	1.4%Prev: 0.9%	1,929,931 SH	Increased-17,443 SH
AMYLYX PHARMACEUTICALS INC	COM	$6.0M	0.3%Prev: 0.4%	499,764 SH	Decreased
APELLIS PHARMACEUTICALS INC	COM	$3.8M	0.2%Prev: 0.1%	150,500 SH	Increased+58,500 SH
ARCELLX INC	COMMON STOCK	$11.1M	0.6%Prev: 0.9%	169,859 SH	Decreased-9,123 SH
ARCUS BIOSCIENCES INC	COM	$4.3M	0.2%	180,000 SH	New
ARDELYX INC	COM	$13.4M	0.7%Prev: 0.7%	2,299,473 SH	Increased+13,200 SH
ARGENX SE	SPONSORED ADR	$86.8M	4.5%Prev: 6.2%	103,250 SH	Decreased-39,500 SH
ASCENDIS PHARMA A/S	SPONSORED ADR	$43.4M	2.2%Prev: 2.5%	203,500 SH	Increased-11,000 SH
AZENTA INC	COM	$18.9M	1.0%Prev: 0.9%	569,100 SH	Increased+28,700 SH
BICARA THERAPEUTICS INC	COM	$7.2M	0.4%Prev: 0.3%	429,095 SH	Increased+58,429 SH
BOSTON SCIENTIFIC CORP	COM	$38.0M	2.0%Prev: 2.1%	399,050 SH	Increased+38,800 SH
BRIDGEBIO PHARMA INC	COM	$7.9M	0.4%Prev: 0.3%	103,500 SH	Increased+18,500 SH
CARIS LIFE SCIENCES INC	COM	$18.5M	1.0%Prev: 1.4%	687,500 SH	Decreased-106,151 SH
CELLDEX THERAPEUTICS INC NEW	COM NEW	$18.8M	1.0%Prev: 1.1%	692,538 SH	Increased-29,000 SH
CENTESSA PHARMACEUTICALS PLC	SPONSORED ADS	$8.1M	0.4%Prev: 0.1%	324,015 SH	Increased+254,775 SH
CIDARA THERAPEUTICS INC	COM NEW	$45.3M	2.3%Prev: 1.4%	204,878 SH	Increased-44,524 SH
COGENT BIOSCIENCES INC	COM	$30.2M	1.5%Prev: 0.8%	849,030 SH	Increased-159,278 SH
COMPASS THERAPEUTICS INC	COM	$21.1M	1.1%Prev: 0.9%	3,927,202 SH	Increased-547,500 SH
CORCEPT THERAPEUTICS INC	COM	$1.7M	0.1%	50,250 SH	New
CYTOKINETICS INC	COM NEW	$2.3M	0.1%	35,853 SH	New
DANAHER CORPORATION	COM	$14.1M	0.7%Prev: 0.7%	61,500 SH	Increased
DEXCOM INC	COM	$23.1M	1.2%Prev: 1.2%	347,300 SH	Increased+30,400 SH
DYNE THERAPEUTICS INC	COM	$17.9M	0.9%Prev: 0.6%	912,955 SH	Increased+88,894 SH
EDAP TMS S A	SPONSORED ADR	$4.2M	0.2%Prev: 0.2%	1,286,500 SH	Increased+16,500 SH
EDWARDS LIFESCIENCES CORP	COM	$7.0M	0.4%Prev: 0.4%	82,500 SH	Increased-5,500 SH
ELI LILLY & CO	COM	$113.3M	5.8%Prev: 4.7%	105,400 SH	Increased
ENLIVEN THERAPEUTICS INC	COM	$12.3M	0.6%Prev: 0.8%	798,405 SH	Decreased+112,298 SH
ERASCA INC	COM	$3.5M	0.2%	951,710 SH	New
EVOLENT HEALTH INC	CL A	$10.7M	0.5%Prev: 1.5%	2,675,000 SH	Decreased-275,000 SH
EXACT SCIENCES CORP	COM	$61.1M	3.1%Prev: 1.9%	601,800 SH	Increased+8,300 SH
EYEPOINT INC	COM NEW	$4.7M	0.2%	258,739 SH	New
GOSSAMER BIO INC	COM	$10.1M	0.5%Prev: 0.5%	3,266,960 SH	Increased
GOSSAMER BIO INC	NOTE 5.000% 6/0	$6.6M	0.3%Prev: 0.4%	9,573,000 PRN	Decreased
HEARTFLOW INC	COM	$8.1M	0.4%Prev: 0.5%	277,700 SH	Decreased+27,700 SH
IMMUNOME INC	COM	$7.5M	0.4%	347,666 SH	New
INDIVIOR PLC	ORD	$3.8M	0.2%	105,100 SH	New
INSMED INC	COM PAR $.01	$55.6M	2.8%Prev: 3.2%	319,250 SH	Increased-65,750 SH
INSPIRE MED SYS INC	COM	$12.1M	0.6%Prev: 0.5%	131,000 SH	Increased+20,500 SH
INTUITIVE SURGICAL INC	COM NEW	$46.4M	2.4%Prev: 2.1%	82,000 SH	Increased
IRHYTHM TECHNOLOGIES INC	COM	$41.7M	2.1%Prev: 2.4%	235,000 SH	Increased
JANUX THERAPEUTICS INC	COM	$5.0M	0.3%Prev: 0.3%	358,798 SH	Decreased+148,432 SH
JASPER THERAPEUTICS INC	COM NEW	$2.0M	0.1%Prev: 0.2%	1,100,726 SH	Decreased
JAZZ PHARMACEUTICALS PLC	SHS USD	$298K	0.0%	1,750 SH	New
KYMERA THERAPEUTICS INC	COM	$38.7M	2.0%Prev: 1.5%	496,871 SH	Increased+46,497 SH
LEGEND BIOTECH CORP	SPONSORED ADS	$735K	0.0%	33,800 SH	New
LENZ THERAPEUTICS INC	COM	$4.1M	0.2%Prev: 0.6%	257,460 SH	Decreased+21,233 SH
MADRIGAL PHARMACEUTICALS INC	COM	$81.3M	4.2%Prev: 3.7%	139,618 SH	Increased+1,872 SH
MBX BIOSCIENCES INC	COM	$8.9M	0.5%Prev: 0.3%	282,624 SH	Increased
MERSANA THERAPEUTICS INC	COM	$4.4M	0.2%Prev: 0.1%	152,586 SH	Increased
MINERALYS THERAPEUTICS INC	COM	$15.5M	0.8%Prev: 0.9%	427,596 SH	Increased+19,283 SH
MIRUM PHARMACEUTICALS INC	COM	$60.2M	3.1%Prev: 3.3%	762,294 SH	Increased+1,168 SH
MOONLAKE IMMUNOTHERAPEUTICS	CLASS A ORD	$813K	0.0%Prev: 0.0%	61,700 SH	Increased+33,500 SH
NEUROCRINE BIOSCIENCES INC	COM	$17.8M	0.9%Prev: 0.7%	125,500 SH	Increased+35,750 SH
NEUROGENE INC	COM	$2.1M	0.1%Prev: 0.1%	104,339 SH	Increased
NEWAMSTERDAM PHARMA COMPANY	ORDINARY SHARES	$20.7M	1.1%Prev: 1.0%	588,794 SH	Increased-38,735 SH
NUVATION BIO INC	*W EXP 02/10/202	$44K	0.0%Prev: 0.0%	134,028 SH	Increased
OCULAR THERAPEUTIX INC	COM	$4.2M	0.2%Prev: 0.2%	345,820 SH	Increased+45,820 SH
OLEMA PHARMACEUTICALS INC	COM	$2.5M	0.1%	98,240 SH	New
OMADA HEALTH INC	COM	$11.7M	0.6%Prev: 1.2%	740,000 SH	Decreased-179,950 SH
PENUMBRA INC	COM	$37.5M	1.9%Prev: 1.8%	120,500 SH	Increased
PHARVARIS N V	COM	$17.3M	0.9%Prev: 0.9%	623,402 SH	Increased
PHREESIA INC	COM	$14.8M	0.8%Prev: 1.0%	876,600 SH	Decreased+127,484 SH
PTC THERAPEUTICS INC	COM	$4.7M	0.2%	61,879 SH	New
RAPT THERAPEUTICS INC	COM NEW	$7.2M	0.4%	213,731 SH	New
REGENERON PHARMACEUTICALS	COM	$7.8M	0.4%Prev: 0.4%	10,100 SH	Increased-1,200 SH
REVOLUTION MEDICINES INC	COM	$106.4M	5.5%Prev: 3.6%	1,335,270 SH	Increased
RHYTHM PHARMACEUTICALS INC	COM	$74.4M	3.8%Prev: 4.2%	695,010 SH	Increased-22,092 SH
ROIVANT SCIENCES LTD	SHS	$1.9M	0.1%	88,750 SH	New
SCHOLAR ROCK HLDG CORP	COM	$32.3M	1.7%Prev: 1.7%	733,477 SH	Increased-60,656 SH
SIONNA THERAPEUTICS INC	COM	$4.1M	0.2%Prev: 0.2%	99,429 SH	Increased
SOLENO THERAPEUTICS INC	COM	$11.4M	0.6%Prev: 0.6%	247,053 SH	Increased+92,525 SH
SPDR SERIES TRUST	STATE STREET SPD	$27.1M	1.4%	222,000 SH	New
STRUCTURE THERAPEUTICS INC	SPONSORED ADS	$52.0M	2.7%Prev: 1.6%	748,236 SH	Increased-202,918 SH
SUMMIT THERAPEUTICS INC	COM	$12.4M	0.6%Prev: 0.9%	710,000 SH	Decreased
SURGERY PARTNERS INC	COM	$4.8M	0.2%	310,000 SH	New
TALPHERA INC	COM NEW	$4.1M	0.2%Prev: 0.2%	3,589,186 SH	Increased
TANGO THERAPEUTICS INC	COM	$3.4M	0.2%	386,915 SH	New
TARSUS PHARMACEUTICALS INC	COM	$21.3M	1.1%Prev: 1.0%	260,344 SH	Increased-28,000 SH
TENET HEALTHCARE CORP	COM NEW	$24.8M	1.3%Prev: 1.5%	125,000 SH	Decreased
TERNS PHARMACEUTICALS INC	COM	$4.4M	0.2%	108,481 SH	New
TEVA PHARMACEUTICAL INDS LTD	SPONSORED ADS	$1.4M	0.1%	45,500 SH	New
THERAVANCE BIOPHARMA INC	COM	$3.9M	0.2%	208,771 SH	New
THERMO FISHER SCIENTIFIC INC	COM	$5.8M	0.3%Prev: 0.3%	10,000 SH	Increased
TRAVERE THERAPEUTICS INC	COM	$84.5M	4.3%Prev: 3.0%	2,210,322 SH	Increased+45,549 SH
ULTRAGENYX PHARMACEUTICAL IN	COM	$29.1M	1.5%Prev: 2.2%	1,267,241 SH	Decreased+20,900 SH
UNITEDHEALTH GROUP INC	COM	$13.5M	0.7%	40,800 SH	New
VAXCYTE INC	COM	$2.2M	0.1%Prev: 0.0%	47,000 SH	Increased+35,900 SH
VERA THERAPEUTICS INC	CL A	$28.8M	1.5%Prev: 1.0%	568,579 SH	Increased-48,817 SH
XENON PHARMACEUTICALS INC	COM	$35.3M	1.8%Prev: 2.0%	787,788 SH	Increased-63,956 SH
ZAI LAB LTD	ADR	$14.3M	0.7%Prev: 1.6%	811,546 SH	Decreased+20,353 SH
ZENAS BIOPHARMA INC	COM	$18.2M	0.9%Prev: 0.8%	502,077 SH	Increased-78,600 SH

Sold (vs prior filing)

AKERO THERAPEUTICS INC — $29.7M
APPLIED THERAPEUTICS INC — $1.3M
CHARLES RIV LABS INTL INC — $422K
COMPUGEN LTD — $20K
EYEPOINT PHARMACEUTICALS INC — $451K
IMMUNOVANT INC — $1.2M
KORRO BIO INC — $1.7M
MEREO BIOPHARMA GROUP PLC — $9.4M
MERUS N V — $56.2M
NOVAVAX INC — $390K
PERSPECTIVE THERAPEUTICS INC — $1.5M
PROTHENA CORP PLC — $248K
SPDR SERIES TRUST — $15.2M
WEST PHARMACEUTICAL SVSC INC — $2.6M

All filings

Open a filing on Jive Data

Filing Date	Quarter	Form	Accession	Portfolio	Filing
Feb 17, 2026	Q4 2025	13F-HR	0001172661-26-000917	$1.95B	View
Nov 14, 2025	Q3 2025	13F-HR	0001172661-25-004882	$1.71B	View
Aug 14, 2026	Q2 2026