| ACCURAY INC | COM | $1.2M | 0.3%Prev: 0.5% | 1,395,508 SH | Decreased+173,150 SH |
| ADC THERAPEUTICS SA | SHS | $272K | 0.1%Prev: 0.1% | 77,081 SH | Decreased-45,000 SH |
| ADICET BIO INC | COM NEW | $790K | 0.2% | 93,812 SH | New |
| ALECTOR INC | COM | $1.4M | 0.3%Prev: 0.6% | 908,351 SH | Decreased+110,000 SH |
| ALIGN TECHNOLOGY INC | COM | $2.5M | 0.6%Prev: 0.3% | 16,000 SH | Increased+5,000 SH |
| ALKERMES PLC | SHS | $3.6M | 0.8%Prev: 1.0% | 130,248 SH | Decreased-4,500 SH |
| ALLOGENE THERAPEUTICS INC | COM | $1.9M | 0.4%Prev: 0.4% | 1,380,118 SH | Increased |
| ANNEXON INC | COM | $1.4M | 0.3% | 272,812 SH | New |
| AQUESTIVE THERAPEUTICS INC | COM | $2.4M | 0.6%Prev: 0.7% | 375,915 SH | Decreased-136,674 SH |
| ARCUS BIOSCIENCES INC | COM | $10.3M | 2.4%Prev: 2.1% | 431,329 SH | Increased-196,297 SH |
| ARS PHARMACEUTICALS INC | COM | $2.2M | 0.5%Prev: 0.3% | 190,065 SH | Increased+49,565 SH |
| ASCENDIS PHARMA A/S | NOTE 2.250% 4/0 | $5.5M | 1.3%Prev: 1.3% | 4,000,000 PRN | Increased |
| ASCENDIS PHARMA A/S | SPONSORED ADR | $6.0M | 1.4%Prev: 1.6% | 28,177 SH | Decreased-5,000 SH |
| ASTRIA THERAPEUTICS INC | COM | $4.0M | 0.9%Prev: 0.6% | 304,775 SH | Increased-15,000 SH |
| ATRICURE INC | COM | $23.6M | 5.5%Prev: 5.2% | 597,431 SH | Increased+5,158 SH |
| AUTOLUS THERAPEUTICS PLC | SPON ADS | $357K | 0.1%Prev: 0.1% | 179,316 SH | Increased |
| AXOGEN INC | COM | $15.6M | 3.6%Prev: 3.3% | 476,826 SH | Increased-265,456 SH |
| BICARA THERAPEUTICS INC | COM | $4.4M | 1.0%Prev: 1.2% | 261,583 SH | Decreased-55,418 SH |
| BICYCLE THERAPEUTICS PLC | SPONSORED ADS | $457K | 0.1%Prev: 0.1% | 64,492 SH | Decreased |
| BIOCRYST PHARMACEUTICALS INC | COM | $3.3M | 0.8%Prev: 0.4% | 418,255 SH | Increased+200,000 SH |
| BIOHAVEN LTD | COM | $10.8M | 2.5%Prev: 0.9% | 955,235 SH | Increased+720,000 SH |
| BIONTECH SE | SPONSORED ADS | $666K | 0.2%Prev: 0.2% | 7,000 SH | Decreased |
| BRAINSWAY LTD | SPONSORED ADS | $247K | 0.1%Prev: 0.2% | 12,965 SH | Decreased-44,001 SH |
| CELLDEX THERAPEUTICS INC NEW | COM NEW | $1.9M | 0.4%Prev: 0.2% | 68,518 SH | Increased+44,000 SH |
| CENTURY THERAPEUTICS INC | COM | $2.8M | 0.6%Prev: 0.2% | 2,793,586 SH | Increased+1,089,354 SH |
| COMPASS PATHWAYS PLC | SPONSORED ADS | $5.6M | 1.3%Prev: 1.1% | 811,046 SH | Increased |
| COMPUGEN LTD | ORD | $417K | 0.1%Prev: 0.1% | 272,402 SH | Increased |
| CYBIN INC | COM NEW | $3.7M | 0.9% | 455,018 SH | New |
| CYTOKINETICS INC | COM NEW | $23.6M | 5.5%Prev: 5.4% | 370,997 SH | Increased-23,943 SH |
| DAY ONE BIOPHARMACEUTICALS I | COM | $9.3M | 2.2%Prev: 1.7% | 999,163 SH | Increased |
| DENALI THERAPEUTICS INC | COM | $5.3M | 1.2%Prev: 0.6% | 318,500 SH | Increased+150,000 SH |
| DEXCOM INC | COM | $5.9M | 1.4%Prev: 1.1% | 88,279 SH | Increased+22,727 SH |
| EDGEWISE THERAPEUTICS INC | COM | $4.0M | 0.9%Prev: 0.9% | 159,736 SH | Increased-54,000 SH |
| ENGENE HOLDINGS INC | COM | $1.5M | 0.3% | 163,645 SH | New |
| ERASCA INC | COM | $947K | 0.2%Prev: 0.2% | 254,436 SH | Increased-95,564 SH |
| FATE THERAPEUTICS INC | COM | $540K | 0.1% | 550,000 SH | New |
| FOGHORN THERAPEUTICS INC | COM | $685K | 0.2%Prev: 0.2% | 126,859 SH | Increased |
| GALAPAGOS NV | SPON ADR | $4.3M | 1.0%Prev: 1.1% | 130,175 SH | Decreased |
| IDEAYA BIOSCIENCES INC | COM | $17.5M | 4.1%Prev: 3.6% | 506,740 SH | Increased-33,183 SH |
| IMMATICS NV | SHS | $2.7M | 0.6%Prev: 0.5% | 261,138 SH | Increased+26,138 SH |
| IMMUNOVANT INC | COM | $3.8M | 0.9%Prev: 0.8% | 150,524 SH | Increased-40,969 SH |
| INOGEN INC | COM | $5.6M | 1.3%Prev: 1.2% | 827,071 SH | Increased+221,446 SH |
| INSPIRE MEDICAL SYSTEMS INC | COM | $793K | 0.2%Prev: 0.3% | 8,600 SH | Decreased-8,600 SH |
| INSULET CORP | COM | $2.0M | 0.5%Prev: 0.5% | 6,870 SH | Decreased |
| ISHARES NASDAQ BIOTECH INDX | ETF | $11.5M | 2.7%Prev: 3.7% | 68,095 SH | Decreased-34,405 SH |
| KALVISTA PHARMACEUTICALS INC | COM | $5.8M | 1.3%Prev: 1.3% | 356,802 SH | Increased-65,929 SH |
| KARYOPHARM THERAPEUTICS | COM NEW | $375K | 0.1% | 51,000 SH | New |
| KURA ONCOLOGY INC | COM | $2.5M | 0.6%Prev: 1.0% | 235,868 SH | Decreased-227,500 SH |
| LARIMAR THERAPEUTICS INC | COM | $3.6M | 0.8%Prev: 0.8% | 939,164 SH | Increased-88,600 SH |
| LEXEO THERAPEUTICS INC | COM | $3.4M | 0.8%Prev: 0.6% | 340,859 SH | Increased-17,224 SH |
| MAPLIGHT THERAPEUTICS INC | COM | $2.5M | 0.6% | 143,764 SH | New |
| MBX BIOSCIENCES INC | COM | $5.2M | 1.2%Prev: 0.4% | 165,265 SH | Increased+80,265 SH |
| MEDIWOUND LTD | SHS NEW | $2.1M | 0.5%Prev: 0.5% | 113,612 SH | Increased |
| MINERALYS THERAPEUTICS INC | COM | $1.4M | 0.3%Prev: 0.8% | 38,490 SH | Decreased-45,000 SH |
| NEKTAR THERAPEUTICS | COM NEW | $3.2M | 0.7%Prev: 0.8% | 74,998 SH | Increased+20,000 SH |
| NEUROCRINE BIOSCIENCES INC | COM | $10.0M | 2.3%Prev: 2.4% | 70,615 SH | Increased |
| NEUROGENE INC | COM | $576K | 0.1%Prev: 0.1% | 27,974 SH | Increased-2,401 SH |
| ORCHESTRA BIOMED HOLDINGS INC | COM | $526K | 0.1%Prev: 0.2% | 126,841 SH | Decreased-236,795 SH |
| ORIC PHARMACEUTICALS INC | COM | $1.2M | 0.3%Prev: 0.3% | 141,045 SH | Decreased+36,374 SH |
| PERSPECTIVE THERAPEUTICS INC | COM NEW | $138K | 0.0% | 50,000 SH | New |
| POLYPID LTD | COM | $902K | 0.2%Prev: 0.2% | 207,900 SH | Increased |
| PROCEPT BIOROBOTICS CORP | COM | $3.8M | 0.9% | 120,000 SH | New |
| PROFOUND MEDICAL CORP | COM NEW | $2.2M | 0.5% | 285,710 SH | New |
| PROQR THERAPEUTICS N V | SHS EURO | $3.2M | 0.7%Prev: 0.8% | 1,567,561 SH | Decreased |
| RAPPORT THERAPEUTICS INC | COM | $2.3M | 0.5%Prev: 0.6% | 75,000 SH | Increased |
| REVOLUTION MEDICINES INC | COM | $48.1M | 11.2%Prev: 7.6% | 604,514 SH | Increased-52,662 SH |
| SPDR S&P BIOTECH ETF | ETF | $41.0M | 9.5%Prev: 9.9% | 336,505 SH | Increased-65,000 SH |
| STEREOTAXIS INC | COM NEW | $31.5M | 7.3%Prev: 10.5% | 13,680,554 SH | Decreased |
| STOKE THERAPEUTICS INC | COM | $3.5M | 0.8%Prev: 1.0% | 108,875 SH | Decreased-60,916 SH |
| STRUCTURE THERAPEUTICS INC | SPONSORED ADS | $2.6M | 0.6%Prev: 0.4% | 37,000 SH | Increased-22,000 SH |
| SYNDAX PHARMACEUTICALS INC | COM | $5.8M | 1.4%Prev: 1.9% | 277,855 SH | Decreased-222,847 SH |
| TANDEM DIABETES CARE INC | COM NEW | $7.8M | 1.8%Prev: 1.1% | 355,208 SH | Increased |
| TELA BIO INC | COM | $1.7M | 0.4%Prev: 0.5% | 1,441,029 SH | Decreased |
| ULTRAGENYX PHARMACEUTICAL INC | COM | $368K | 0.1% | 16,000 SH | New |
| VERRICA PHARMACEUTICALS INC | COM SHS | $1.4M | 0.3% | 173,451 SH | New |
| VIKING THERAPEUTICS INC | COM | $2.1M | 0.5%Prev: 0.4% | 59,516 SH | Increased-5,000 SH |
| XENON PHARMACEUTICALS INC | COM | $12.9M | 3.0%Prev: 2.9% | 287,939 SH | Increased |