X0508 4 2026-02-05 0001778922 SpyGlass Pharma, Inc. SGP 0002106895 Dennewill James Robert Jr. C/O SPYGLASS PHARMA, INC. 27061 ALISO CREEK RD., SUITE 100 ALISO VIEJO CA 92656 false true false false Chief Operating Officer 0 Stock Option (right to buy) 16 2026-02-05 4 A 0 105000 0 A 2036-02-05 Common Stock 105000 105000 D Subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2026 Equity Incentive Plan) through each applicable date, twenty five percent (25%) of the shares subject to the option shall vest on the one (1) year anniversary of the Vesting Commencement Date, and one forty-eighth (1/48th) of the shares subject to the option shall vest each month thereafter on the same day of the month as the Vesting Commencement Date (and if there is no corresponding day, on the last day of the month). "Vesting Commencement Date" shall mean February 5, 2026. /s/ Brian Aukshunas, as Attorney-in-Fact 2026-02-09