X0508 4 2026-02-26 0 0002019410 Caris Life Sciences, Inc. CAI 0002071948 Fredrickson David Paul C/O CARIS LIFE SCIENCES, INC. 750 W. JOHN CARPENTER FREEWAY, SUITE 800 IRVING TX 75039 1 0 0 0 0 Common Stock 2026-02-26 4 A 0 2492 20.06 A 18621 D Shares issued in lieu of cash compensation for 2025 board retainer fees. Number of shares determined by dividing the cash retainer earned by the ten trading day average of the daily volume weighted average price per share through and including February 25, 2026. /s/ J. Russel Denton, Attorney-in-Fact 2026-02-27