X0508 4 2025-12-16 0001346830 Tvardi Therapeutics, Inc. TVRD 0002064884 Alibhai Imran Nizamudin C/O TVARDI THERAPEUTICS, INC. 3 SUGAR CREEK CTR BLVD, STE 525 SUGAR LAND TX 77478 true true false false Chief Executive Officer 0 Employee Stock Option (right to buy) 4.20 2025-12-16 4 A 0 47500 0 A 2035-12-16 Common Stock 47500 47500 D 25% of the shares subject to the option shall vest on December 16, 2026, and the balance of the shares subject to the option shall vest in equal monthly installments over the following 36 months, subject to the Reporting Person's continuous service through each applicable vesting date. /s/ Dan Conn, Attorney-in-Fact 2025-12-18