X0508 4 2026-01-22 0001802665 Harmony Biosciences Holdings, Inc. HRMY 0002064712 Zaeske Adam H. C/O HARMONY BIOSCIENCES HOLDINGS, INC. PLYMOUTH MEETING PA 19462 false true false false CHIEF COMMERCIAL OFFICER 0 Stock Option 36.76 2026-01-22 4 A 0 56900 0 A 2036-01-22 Common Stock 56900 56900 D Restricted Stock Units 2026-01-22 4 A 0 16200 0 A Common Stock 16200 16200 D The stock option vests with respect to 25% of the underlying shares on January 22, 2027, with the remaining shares vesting ratably on a quarterly basis thereafter until the fourth anniversary of the grant date, subject to the Reporting Person's continued service through each applicable vesting date. The restricted stock units shall vest in four equal annual installments beginning on January 22, 2027, subject to the Reporting Person's continued service through each applicable vesting date. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date. /s/ Christian Ulrich, Attorney-in-Fact 2026-01-26