X0508 4 2026-03-02 0001842295 Maze Therapeutics, Inc. MAZE 0002050422 Bachrodt Amy C/O MAZE THERAPEUTICS, INC. 171 OYSTER POINT BOULEVARD, SUITE 300 SOUTH SAN FRANCISCO CA 94080 false true false false SVP, Finance 1 Common Stock 2026-03-02 4 M 0 5000 10.42 A 17965 D Common Stock 2026-03-02 4 S 0 1300 44.4414 D 16665 D Common Stock 2026-03-02 4 S 0 3700 45.4694 D 12965 D Stock Option (Right to Buy) 10.42 2026-03-02 4 M 0 5000 0 D 2034-12-08 Common Stock 5000 36333 D Stock Option (Right to Buy) 45.61 2026-03-02 4 A 0 32000 0 A 2036-03-01 Common Stock 32000 32000 D Restricted Stock Units 2026-03-02 4 A 0 16000 0 A Common Stock 16000 16000 D This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $44.01 to $44.91 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and in footnote 3 of this Form 4. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.03 to $45.99 per share, inclusive. The option vested or vests as to 1/48th of the total award monthly, with the first tranche vested on January 1, 2025, and each subsequent tranche vesting on the monthly anniversary thereof, subject to the reporting person's continued service to the Issuer on each vesting date. The option award shall vest as to 1/48 of the total award monthly, with the first tranche vesting on April 1, 2026, subject to the reporting person's continued service to the Issuer on each vesting date. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock upon settlement. The restricted stock unit award shall vest in ratable increments of 1/4 of the total award, with the first tranche vesting on March 1, 2027, and vesting thereafter on the one year anniversary of such date, subject to the reporting person's continued service to the Issuer on each vesting date. These restricted stock units do not expire; they either vest or are cancelled prior to the vesting date. /s/ Courtney Phillips, as attorney-in-fact 2026-03-03