X0609 4 2026-09-02 0001842295 Maze Therapeutics, Inc. MAZE 0002050167 Dandekar Atul false C/O MAZE THERAPEUTICS, INC. 171 OYSTER POINT BOULEVARD, SUITE 300 SOUTH SAN FRANCISCO CA 94080 false true false false CSBO 0 Common Stock 2026-09-02 4 S 0 2800 26.3760 D 35950 D Common Stock 2026-09-02 4 S 0 391 27.1211 D 35559 D Common Stock 2026-09-03 4 S 0 3207 26.0133 D 32352 D Common Stock 2026-09-03 4 S 0 36 25.8100 D 32316 D The reported transaction represents shares of the Issuer's Common Stock sold to satisfy tax withholding obligations incurred in connection with the vesting of restricted stock units. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $26.03 to $27.00 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and in footnotes 3 and 4 of this Form 4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.055 to $27.40 per share, inclusive. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $25.743 to $26.65 per share, inclusive. /s/ Courtney Phillips, as attorney-in-fact 2026-09-04