X0609 4 2026-08-28 0001842295 Maze Therapeutics, Inc. MAZE 0002050167 Dandekar Atul false C/O MAZE THERAPEUTICS, INC. 171 OYSTER POINT BOULEVARD, SUITE 300 SOUTH SAN FRANCISCO CA 94080 false true false false CSBO 1 Common Stock 2026-08-28 4 M 0 7500 10.42 A 33750 D Common Stock 2026-08-28 4 S 0 7500 27.5765 D 26250 D Stock Option (Right to Buy) 10.42 2026-08-28 4 M 0 7500 0 D 2031-04-11 Common Stock 7500 14143 D This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 29, 2025. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $27.31 to $28.01 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The option is fully vested. Pursuant to the terms of the reporting person's award agreement with the Issuer, the award became fully vested on March 17, 2025. /s/ Courtney Phillips, as attorney-in-fact 2026-08-31