X0508 4 2026-01-29 0 0001906324 QuidelOrtho Corp QDEL 0002040321 Siegrist Jonathan Philip 9975 SUMMERS RIDGE ROAD SAN DIEGO CA 92121 0 1 0 0 EVP of R&D & CTO 0 Common Stock 2026-01-29 4 A 0 2448 0 A 14428 D Common Stock 2026-01-29 4 F 0 1009 27.41 D 13419 D Restricted Stock Units 2026-01-29 4 M 0 2448 0 D Common Stock 2448 4898 D Reflects release of restricted stock units that were previously reported on a Form 4. Disposition of shares, as set forth above, was in connection with the Issuer's withholding of common shares to satisfy tax withholding obligations related to the issuance of common shares upon release of restricted stock units. Each restricted stock unit represents the right to receive one share of QuidelOrtho Corporation common stock. 2,448 shares vested on January 29, 2026; the remaining 4,898 shares will vest in equal installments on January 29, 2027 and January 29, 2028. /s/ Jennifer Ahn, attorney-in-fact for Jonathan P. Siegrist 2026-02-02