X0508 4 2026-02-18 0001907108 Lexeo Therapeutics, Inc. LXEO 0002024096 Otero Jose Manuel C/O LEXEO THERAPEUTICS, INC. 345 PARK AVENUE SOUTH, FLOOR 6 NEW YORK NY 10010 false true false false Chief Operating Officer 0 Common Stock 2026-02-18 4 S 0 3016 6.3972 D 125460 D Represents a sale to cover tax obligations on the release of restricted stock units ("RSUs"). This transaction was executed in multiple trades at prices ranging from $6.22 to $6.47. The price reported above reflects the weighted average sale price. The Reporting Person undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate sale price. Includes 104,216 Restricted Stock Units. /s/ Carole Rosenberg, Attorney-in-Fact 2026-02-20