X0508 4 2026-02-02 0001217234 CareDx, Inc. CDNA 0002019976 Novack Jeffrey Adam C/O CAREDX, INC. 8000 MARINA BOULEVARD, 4TH FLOOR BRISBANE CA 94005 false true false false Secretary and General Counsel 0 Common Stock 2026-02-02 4 A 0 33000 0 A 130925 D Common Stock 2026-02-02 4 A 0 4342 0 A 135267 D Common Stock 2026-02-02 4 F 0 2492 20.42 D 132775 D Common Stock 2026-02-02 4 F 0 2970 20.42 D 129805 D Common Stock 2026-02-03 4 S 0 4441 20.5553 D 125364 D The reported securities are represented by restricted stock units ("RSUs"), of which one-third will vest on April 6, 2027 and the remaining two-thirds will vest in equal quarterly installments thereafter on the last day of each of the subsequent eight quarters, rounded down to the nearest whole share until the last such installment, such that one-hundred percent of the RSUs will be vested on the third anniversary of April 6, 2027, subject to the Reporting Person's continuous employment on each applicable vesting date. The reported securities were subject to a performance restricted stock unit ("PRSU") award that was initially granted on February 1, 2025, and were earned by the Reporting Person upon the achievement of certain performance criteria as certified by the Compensation and Human Capital Committee of the Issuer's Board of Directors on February 2, 2026. These shares were withheld by the Issuer in order to satisfy certain tax withholding obligations in connection with the issuance of shares upon the vesting of PRSUs. These shares were withheld by the Issuer in order to satisfy certain tax withholding obligations in connection with the issuance of shares upon the vesting of RSUs. The transaction reported in this row was effected pursuant to a Rule 10b5-1 trading plan, adopted by the Reporting Person on September 4, 2025. /s/ Jeffrey Adam Novack 2026-02-04