X0609 4 2026-08-06 0001604821 Natera, Inc. NTRA 0002010135 Fesko John false C/O NATERA, INC. 13011 MCCALLEN PASS BUILDING A SUITE 100 AUSTIN TX 78753 false true false false PRESIDENT, CHIEF BUS. OFFICER 1 Common Stock 2026-08-06 4 A 0 20000 0 A 203774 D Common Stock 2026-08-10 4 S 0 6517 321.53 D 197257 D On August 12, 2022, the Reporting Person was granted performance-based Restricted Stock Units (RSUs) covering 50,000 shares of Common Stock vesting in tranches upon the Issuer achieving certain specified financial and operating metrics. On August 6, 2026, the achievement of milestones for the vesting of RSUs covering 20,000 shares of Common Stock was certified. The sale of shares was effected in order to satisfy tax withholding and remittance obligations in connection with the vesting of RSUs and made pursuant to a written instruction that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act contained in the Reporting Person's Stock Unit Agreement granted on August 12, 2022. /s/ Tami Chen, Attorney-in-Fact 2026-08-28