X0508 4 2026-01-22 0001802665 Harmony Biosciences Holdings, Inc. HRMY 0002009762 Budur Kumar 630 W GERMANTOWN PIKE PLYMOUTH MEETING PA 19462 false true false false CHIEF MEDICAL OFFICER 0 Common Stock 2026-01-24 4 M 0 2188 0 A 2188 D Common Stock 2026-01-24 4 F 0 1153 36.82 D 1035 D Common Stock 2026-01-25 4 M 0 2662 0 A 2662 D Common Stock 2026-01-25 4 F 0 1372 36.82 D 1290 D Stock Option 36.76 2026-01-22 4 A 0 42600 0 A 2036-01-22 Common Stock 42600 42600 D Restricted Stock Units 2026-01-22 4 A 0 12200 0 A Common Stock 12200 12200 D Restricted Stock Units 2026-01-24 4 M 0 2188 0 D Common Stock 2188 4175 D Restricted Stock Units 2026-01-25 4 M 0 2662 0 D Common Stock 2662 7988 D Shares withheld by the Issuer to satisfy required income tax withholdings pursuant to the vesting of restricted stock units on their scheduled vesting date. The stock option vests with respect to 25% of the underlying shares on January 22, 2027, with the remaining shares vesting ratably on a quarterly basis thereafter until the fourth anniversary of the grant date, subject to the Reporting Person's continued service through each applicable vesting date. The restricted stock units shall vest in four equal annual installments beginning on January 22, 2027, subject to the Reporting Person's continued service through each applicable vesting date. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date. This award of restricted stock units was previously granted on January 24, 2024. The restricted stock units shall vest in four equal annual installments beginning on January 24, 2025, subject to the Reporting Person's continued service through each applicable vesting date. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date. This award of restricted stock units was previously granted on January 25, 2025. The restricted stock units shall vest in four equal annual installments beginning on January 25, 2026, subject to the Reporting Person's continued service through each applicable vesting date. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock and has no expiration date. /s/ Christian Ulrich, Attorney-in-Fact 2026-01-26