X0609 4 2026-09-11 0001472012 Immunome Inc. IMNM 0001993684 Higgins Jack false C/O IMMUNOME, INC. 18702 N. CREEK PARKWAY, SUITE 100 BOTHELL WA 98011 false true false false Chief Scientific Officer 1 Common Stock 2026-09-11 4 M 0 18000 1.35 A 78250 D Common Stock 2026-09-11 4 S 0 13200 25.32 D 65050 D Common Stock 2026-09-11 4 G 0 8800 0 D 56250 D Common Stock 1000 I As Custodian for Child 1 Common Stock 1000 I As Custodian for Child 2 Common Stock 1000 I As Custodian for Child 3 Employee Stock Option (right to buy) 1.35 2026-09-11 4 M 0 18000 0 A 2032-06-23 Common Stock 18000 133840 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 19, 2025. The Reporting Person serves as a custodian of a custodial account for his child pursuant to the Uniform Transfer to Minors Act. The Reporting Person disclaims beneficial ownership of these shares, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of such shares for purposes of Section 16 or for any other purpose. 25% of the shares subject to the options vested on May 1, 2023, and one-thirty-sixth (1/36th) of the remaining shares subject to the options vests every month thereafter, subject to the Reporting Person's continuous service through each such vesting date. /s/ Sandra Stoneman, Attorney-in-Fact 2026-09-15