X0609 4 2026-10-08 0 0001599298 Summit Therapeutics Inc. SMMT 0001890784 Anand Bhaskar false C/O SUMMIT THERAPEUTICS INC. 601 BRICKELL KEY DRIVE, SUITE 1000 MIAMI FL 33131 0 1 0 0 Chief Accounting Officer 0 Common Stock 2026-10-08 4 A 0 100000 0 A 261047 D Restricted stock units granted under the Issuer's Amended and Restated 2020 Stock Incentive Plan. The restricted stock units vest on October 8, 2029, subject to the Reporting Person continuing his employment with the Issuer, and will entitle the Reporting Person to one share of the Issuer's common stock for each restricted stock unit that vests. Holdings include shares previously acquired through exempt transactions pursuant to the Issuer's employee stock purchase plan. /s/ Bhaskar Anand 2026-10-14