X0609 4 2026-05-18 0001818382 Humacyte, Inc. HUMA 0001817285 Constantino Michael T. false 2525 EAST NORTH CAROLINA HIGHWAY 54 DURHAM NC 27713 true false false false false Common Stock 2026-05-18 4 P false 11000 0.8945 A 43950 D The price is a weighted average price. The shares were purchased in multiple transactions at per share prices ranging from $0.8922 to $0.8958. The Reporting Person undertakes to provide upon request to the SEC staff, or any stockholder of the Issuer, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote. /s/ Michael T. Constantino by Dale A. Sander as Attorney-in-Fact 2026-05-20