X0508 4 2025-11-03 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001817217 van Houte Hans C/O NURIX THERAPEUTICS, INC. 1700 OWENS STREET, SUITE 205 SAN FRANCISCO CA 94158 0 1 0 0 Chief Financial Officer 1 Common Stock 2025-11-03 4 S 0 6284 12.5607 D 37592 D This transaction was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person. Represents the weighted average sale price. The lowest price at which shares were sold was $12.32 and the highest price at which shares were sold was $13.14. The Reporting Person undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or its stockholders, full information regarding the total number of shares sold at each separate price within the range set forth herein. /s/ Daniel Burbach, as Attorney-in-Fact for Hans van Houte 2025-11-03