X0508 4 2025-12-18 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001817199 Ring Christine C/O NURIX THERAPEUTICS, INC. 1600 SIERRA POINT PKWY BRISBANE CA 94005 0 1 0 0 Chief Legal Officer 1 Common Stock 2025-12-18 4 M 0 3760 1.86 A 54657 D Common Stock 2025-12-18 4 S 0 3560 17.8661 D 51097 D Common Stock 2025-12-18 4 S 0 200 18.555 D 50897 D Employee Stock Option (right to buy) 1.86 2025-12-18 4 M 0 3760 0 D 2029-09-30 Common Stock 3760 12403 D This transaction was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person. Represents the weighted average sale price. The lowest price at which shares were sold was $17.53 and the highest price at which shares were sold was $18.18. The Reporting Person undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or its stockholders, full information regarding the total number of shares sold at each separate price within the range set forth herein. Represents the weighted average sale price. The lowest price at which shares were sold was $18.55 and the highest price at which shares were sold was $18.56. The Reporting Person undertakes to provide upon request to the staff of the Securities and Exchange Commission, the Issuer or its stockholders, full information regarding the total number of shares sold at each separate price within the range set forth herein. The option vested as to 1/4 of the total shares on September 9, 2020, and then 1/48 of the total shares vested monthly thereafter until the option was fully vested on August 9, 2023. /s/ Daniel Burbach, as Attorney-in-Fact for Christine Ring 2025-12-18