X0508 4 2026-01-16 0 0001232524 Jazz Pharmaceuticals plc JAZZ 0001805688 Pearce Samantha 5TH FL, WATERLOO EXCHANGE WATERLOO RD DUBLIN 4 L2 IRELAND 0 1 0 0 EVP, Chief Commercial Officer 0 Ordinary Shares 2026-01-16 4 A 0 3637 0.0 A 44592 D Ordinary Shares 2026-01-16 4 F 0 1599 171.16 D 42993 D Represents ordinary shares of the Issuer delivered pursuant to the terms of performance share awards made to the reporting person on March 3, 2023. The performance-based vesting requirements applicable to such awards were satisfied on January 16, 2026, which represents the date on which the level of performance attained was certified. The Reporting Person acquired 140 ordinary shares under a Section 423 Employee Stock Purchase Plan on November 28, 2025. Shares withheld from the vesting and distribution of performance share awards to satisfy the reporting person's tax obligations. By: /s/Paz Dizon, as attorney in fact For: Samantha J Pearce 2026-01-21