X0609 4 2026-03-13 0001853921 Scribe Therapeutics, Inc. SCTX 0001781292 Lucas Svetlana false C/O SCRIBE THERAPEUTICS INC. 1150 MARINA VILLAGE PARKWAY ALAMEDA CA 94501 false true false false Chief Business Officer 0 Common Stock 2026-07-23 4 P 0 3000 15 A 3000 I By Spouse Stock Option (Right to Buy) 19.13 2026-03-13 4 A 0 9547 0 A 2036-03-12 Common Stock 9547 9547 D Stock Option (Right to Buy) 15 2026-07-23 4 A 0 109426 0 A 2036-07-22 Common Stock 109426 109426 D Performance-based Stock Option (Right to Buy) 15 2026-07-23 4 A 0 109426 0 A 2036-07-22 Common Stock 109426 109426 D The transaction occurred prior to the Issuer's registration of a class of equity securities under Section 12 of the Exchange Act in connection with the Issuer's initial public offering, and the transaction is reported herein pursuant to Rule 16a-2(a). The option is fully vested. The options will vest as to 1/48 of the total shares monthly over four years, with the first tranche scheduled to vest on August 23, 2026, subject to the Reporting Person's provision of service to the Issuer on each vesting date. The options are eligible to vest upon the achievement of certain market-based performance criteria during a performance period beginning on July 23, 2026 and ending on July 23, 2029, subject to the Reporting Person's provision of service to the Issuer on each vesting date. /s/ David L. Parrot, Attorney-in-Fact 2026-07-27