X0508 4 2026-02-26 0 0001055726 INOVIO PHARMACEUTICALS, INC. INO 0001770390 Humeau Laurent C/O INOVIO PHARMACEUTICALS, INC. 6769 MESA RIDGE RD. SAN DIEGO CA 92121 0 1 0 0 Chief Scientific Officer 0 Common Stock 2026-02-26 4 M 0 5010 A 37632 D Common Stock 2026-02-26 4 F 0 2064 1.79 D 35568 D Common Stock 2026-02-26 4 M 0 7366 A 42934 D Common Stock 2026-02-26 4 F 0 3034 1.79 D 39900 D Restricted Stock Unit 2026-02-26 4 M 0 5010 0 D Common Stock 5010 5009 D Restricted Stock Unit 2026-02-26 4 M 0 7366 0 D Common Stock 7366 14732 D Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 15,029 restricted stock units granted on February 28, 2024 was as follows: 5,010 shares vested on February 26, 2025; 5,010 shares vested on February 26, 2026; and 5,009 shares will vest on February 26, 2027. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both. The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (1) herein. Each restricted stock unit represents a contingent right to receive one share of common stock. The vesting schedule for the 22,098 restricted stock units granted on February 27, 2025 was as follows: 7,366 shares vested on February 26, 2026; 7,366 shares will vest on February 26, 2027; 7,366 shares will vest on February 26, 2028. Vested restricted stock units can be settled in shares of common stock, cash or a combination of both. The transaction reported represents the withholding of shares by the issuer to satisfy the reporting person's tax withholding obligations in connection with the vesting and settlement of the restricted stock unit award reported in the immediately preceding row and described in footnote (3) herein. /s/ Laurent Humeau 2026-02-27