X0508 4 2026-01-22 0 0001746473 PLIANT THERAPEUTICS, INC. PLRX 0001808895 Coulie Bernard C/O PLIANT THERAPEUTICS, INC. 331 OYSTER POINT BOULEVARD SOUTH SAN FRANCISCO CA 94080 1 1 0 0 President and CEO 0 Stock Option (Right to Buy) 1.30 2026-01-22 4 A 0 1230000 0 A 2036-01-22 Common Stock 1230000 1230000 D 1/48th of the shares subject to such option vest and become exercisable in substantially equal installments on each monthly anniversary of January 1, 2026, subject to the Reporting Person's continuous service to the Issuer on each such date. /s/ Jennifer Woo, attorney-in-fact 2026-01-26