X0508 4 2025-08-03 0 0001688757 ESTABLISHMENT LABS HOLDINGS INC. ESTA 0001742429 Chacon Quiros Juan Jose C/O MOTIVA USA LLC 16192 COASTAL HIGHWAY LEWES DE 19958 1 0 0 0 0 Common Shares 2025-08-03 4 A 0 10285 0 A 224433 D Common Shares 1078264 I See Footnote Stock Option (Right to buy) 36.46 2025-08-03 4 A 0 14906 0 A 2026-06-01 2035-05-14 Common Shares 14906 14906 D Represents an award of stock units under the Issuer's 2018 Equity Incentive Plan. One-fourth of the shares subject to the award shall vest on June 1, 2026 and each one-year anniversary thereafter, subject to the Reporting Person continuing as a service provider through such date. The grant was contingent upon execution of a post-employment agreement, which was signed on August 3, 2025. Concurrently, the Reporting Person entered into a consulting agreement effective June 1, 2025. The shares are held by Sariel Group Ltd. The Reporting Person is a shareholder of Sariel Group Ltd and has voting and dispositive power over the shares owned by Sariel Group Ltd. The Reporting Person disclaims beneficial ownership of the shares held by Sariel Group Ltd, except to the extent of his pecuniary interest therein. One-fourth of the shares subject to the option shall vest on June 1, 2026 and each one-year anniversary thereafter, subject to the Reporting Person continuing as a service provider through each such date. /s/ Rajbir S. Denhoy, Chief Financial Officer, by power of attorney 2026-01-09