X0609 4 2026-08-25 0 0001651308 BeOne Medicines Ltd. ONC 0001739452 Wu Xiaobin true C/O BEONE MEDICINES I GMBH AESCHENGRABEN 27, 21ST FLOOR BASEL V8 4051 SWITZERLAND 0 1 0 0 President and COO 1 Ordinary Shares 1270084 D American Depositary Shares 12365 D American Depositary Shares 4000 I By Wife American Depositary Shares 2026-08-25 4 S 0 280 380 D 0 D Each American Depositary Share represents 13 Ordinary Shares. The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 7, 2025. /s/ Chan Henry Lee, as Attorney-in-Fact 2026-08-27