X0609 4 2026-09-24 0 0001314052 ANAVEX LIFE SCIENCES CORP. AVXL 0001655366 Boenisch Sandra false 630 5TH AVENUE, 20TH FLOOR NEW YORK NY 10111 0 1 0 0 PFO & Treasurer 0 Stock Option (Right to Buy) 10.09 2026-09-24 4 A 0 20000 0 A 2026-09-24 2032-06-27 Common Stock 20000 20000 D Stock Option (Right to Buy) 8.57 2026-09-24 4 A 0 25000 0 A 2026-09-24 2033-03-31 Common Stock 25000 25000 D Stock Option (Right to Buy) 5.36 2026-09-24 4 A 0 25000 0 A 2026-09-24 2034-02-20 Common Stock 25000 25000 D Stock Option (Right to Buy) 8.58 2026-09-24 4 A 0 25000 0 A 2026-09-24 2035-03-31 Common Stock 25000 25000 D As described in the Issuer's Current Report on Form 8-K filed with the Securities and Exchange Commission on September 28, 2026, the election of the Issuer's board of directors at the Issuer's 2026 Annual Meeting of Stockholders on September 24, 2026 constituted a "change in control" under the Issuer's incentive plans and Ms. Boenisch's employment agreement and all outstanding and unvested awards previously granted to Ms. Boenisch became immediately vested and exercisable in accordance with the terms of the applicable incentive plan and award agreement under which they were granted, including the following awards which had not been previously reported due to their performance-based vesting terms: 20,000 options at an exercise price of $10.09 granted June 27, 2022, 25,000 options at an exercise price of $8.57 granted March 31, 2023, 25,000 options at an exercise price of $5.36 granted February 20, 2024 and 25,000 options at an exercise price of $8.58 granted March 31, 2025. /s/ Sandra Boenisch 2026-09-28