X0508 4 2026-01-06 0 0001314052 ANAVEX LIFE SCIENCES CORP. AVXL 0001655366 Boenisch Sandra 650 5TH AVENUE, 20TH FLOOR NEW YORK NY 10111 0 1 0 0 PFO & Treasurer 0 Stock Option (Right to Buy) 8.58 2026-01-06 4 A 0 12500 0 A 2026-01-06 2035-03-31 Common Stock 12500 12500 D On March 31, 2025, the reporting person was granted an option to purchase 50,000 shares of common stock. The option vests in four equal tranches based on four performance milestones, one of which was a second regulatory dialogue for blarcamesine. The performance criteria for this milestone was met, resulting in vesting of the option as to 12,500 shares. /s/ Sandra Boenisch 2026-01-09