X0609 4 2026-04-15 0001888886 Structure Therapeutics Inc. GPCR 0001712069 Lang Matthew false C/O STRUCTURE THERAPEUTICS INC. 601 GATEWAY BLVD., SUITE 900 SOUTH SAN FRANCISCO CA 94080 false true false false COO & GC 0 Ordinary Shares 2026-04-15 4 A 0 184614 0 A 184614 D Share option (right to buy) 18.08 2026-04-15 4 A 0 223776 0 A 2036-04-14 Ordinary Shares 223776 223776 D The Ordinary Shares of the Issuer may be represented by American Depositary Shares ("ADSs"). Each ADS represents three Ordinary Shares of the Issuer. Represents the grant of restricted stock units ("RSUs"), each of which represents a contingent right to receive one Ordinary Share of the Issuer. The RSUs vest 1/4th annually on each anniversary of April 15, 2026, subject to Reporting Person's continued service on such dates. The option exercise price per share is equal to the fair market value per Ordinary Share on the grant date based on the trading price of the Issuer's ADSs. One-fourth of the shares vest on the first anniversary of April 15, 2026, and the remaining shares shall vest in thirty-six (36) equal monthly installments thereafter, subject to the Reporting Person's continued service through each such vesting date. /s/ Jun Yoon, Attorney-in-Fact 2026-04-22