X0609 4 2026-08-19 0 0001125345 MACROGENICS INC MGNX 0001706903 Peters Jeffrey Stuart false 9704 MEDICAL CENTER DRIVE ROCKVILLE MD 20850 0 1 0 0 Senior VP, GC, and Secretary 1 Common Stock 2026-08-19 4 S 0 31105 4.15 D 0 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 20, 2026. This transaction was executed in multiple trades at prices ranging from $4.12 to $4.24. The reporting person undertakes to provide to MacroGenics, Inc., any security holder of MacroGenics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range. /s/ Beth A. Smith, Attorney-in-fact 2026-08-20