X0508 4 2025-12-05 0001603454 Celcuity Inc. CELC 0001688319 Buller Richard E 16305 36TH AVE N SUITE 100 MINNEAPOLIS MN 55446 true false false false 0 Common Stock 2025-12-05 4 M 0 3000 5.50 A 9760 I By Trust Common Stock 2025-12-05 4 S 0 1490 105.3398 D 8270 I By Trust Common Stock 2025-12-05 4 S 0 1510 106.0353 D 6760 I By Trust Common Stock 1029 D Stock Option (right to buy) 5.50 2025-12-05 4 M 0 3000 0 D 2029-12-03 Common Stock 3000 1555 I By Trust The Reporting Person and his spouse are the trustees and beneficiaries. The Reporting Person continues to beneficially own these securities held by the trust. The price reported in Column 4 is a weighted average price. These shares of common stock of the issuer were traded in multiple transactions at prices ranging from $105.00 to $105.70, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares of common stock of the issuer were traded in multiple transactions at prices ranging from $106.00 to $106.45, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares traded at each separate price within the range set forth in this footnote. 100% vested. /s/ Griffin D. Foster as Attorney-in-Fact for Richard E. Buller pursuant to Power of Attorney previously filed 2025-12-09