X0508 4 2026-02-07 0 0001434647 ZEVRA THERAPEUTICS, INC. ZVRA 0001681098 McFarlane Neil F. C/O ZEVRA THERAPEUTICS, INC. 1180 CELEBRATION BOULEVARD, SUITE 103 CELEBRATION FL 34747 1 1 0 0 President and CEO 1 Common Stock 2026-02-07 4 M 0 37500 A 401850 D Common Stock 2026-02-09 4 S 0 14625 8.5597 D 387225 D Restricted Stock Unit 2026-02-07 4 M 0 37500 0 D Common Stock 37500 75000 D Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. Adoption date of referenced 10b5-1(c) plan is: 3/21/2025. This transaction was executed in multiple trades at prices ranging from $8.39 to $8.67. The price reported reflects the weighted average sale price. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer or any security holder of the Issuer full information regarding the number of shares and prices at which the transaction was effected. One third of the restricted stock units vested and settled on February 7, 2026. The remaining two thirds of the shares will vest and settle in two equal annual installments thereafter, subject in each case to the Reporting person's continued service through such vesting date. /s/ Timothy J. Sangiovanni, Attorney-in-Fact for Neil F. McFarlane 2026-02-10