X0508 4 2025-11-12 0001070081 PTC THERAPEUTICS, INC. PTCT 0001680329 Reeve Emma C/O PTC THERAPEUTICS, INC. 500 WARREN CORPORATE CENTER DRIVE WARREN NJ 07059 true false false false 1 Common Stock 2025-11-12 4 M 0 7333 46.54 A 13999 D Common Stock 2025-11-12 4 S 0 7333 74.50 D 6666 D Stock Option (Right to Buy) 46.54 2025-11-12 4 M 0 7333 0 D 2035-01-02 Common Stock 7333 1467 D This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on March 4, 2025. This option was granted on January 3, 2025 and vests over one year in twelve equal monthly installments, commencing on February 3, 2025. /s/ Avraham S. Adler, Attorney-in-Fact 2025-11-14