X0609 4 2026-05-15 0001842295 Maze Therapeutics, Inc. MAZE 0001676170 Coloma Jason V false C/O MAZE THERAPEUTICS, INC. 171 OYSTER POINT BOULEVARD, SUITE 300 SOUTH SAN FRANCISCO CA 94080 true true false false Chief Executive Officer 1 Common Stock 2026-05-15 4 S 0 1822 26 D 381073 I Coloma Family Trust Common Stock 2026-05-15 4 S 0 116 26 D 31001 I The Coloma 2021 Irrevocable Trust This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 6, 2026. These securities are directly held by the Coloma Family Trust (the "Family Trust"), for which the reporting person and his spouse serve as co-trustees. These securities are directly held by The Coloma 2021 Irrevocable Trust (the "Irrevocable Trust"), for which the reporting person and his spouse serve as co-trustees. The securities reported on this Form 4 as attributable to the Family Trust and the Irrevocable Trust were incorrectly reported on the reporting person's Form 3 as directly held by the reporting person. This Form 4 corrects his Form 3 and restates the attribution of his holdings. All prior Section 16 reports filed on behalf of the reporting person should be understood to incorporate this correction. /s/ Courtney Phillips, as attorney-in-fact 2026-05-18