X0609 4 2026-05-29 0 0002019410 Caris Life Sciences, Inc. CAI 0001662103 Knowles Jonathan Kenneth Charles false C/O CARIS LIFE SCIENCES, INC. 750 W. JOHN CARPENTER FREEWAY, SUITE 800 IRVING TX 75039 1 0 0 0 0 Common Stock 2026-05-29 4 A 0 1600 15.62 A 308979 D Shares issued in lieu of cash compensation for 2026 board retainer fees. Number of shares determined by dividing the cash retainer earned by the ten trading day average of the daily volume weighted average price per share through and including May 29, 2026. /s/ J. Russel Denton, Attorney-in-Fact 2026-06-02