X0609 4 2026-09-11 0001604821 Natera, Inc. NTRA 0001646382 Rabinowitz Matthew false C/O NATERA, INC. 13011 MCCALLEN PASS BUILDING A SUITE 100 AUSTIN TX 78753 true true false false EXECUTIVE CHAIRMAN 1 Common Stock 2026-09-11 4 S 0 800 325.0075 D 2274594 D Common Stock 2026-09-11 4 S 0 3647 326.1077 D 2270947 D Common Stock 2026-09-11 4 S 0 10556 327.1442 D 2260391 D Common Stock 2026-09-11 4 S 0 17933 327.9724 D 2242458 D Common Stock 2026-09-11 4 S 0 15764 328.9502 D 2226694 D Common Stock 2026-09-11 4 S 0 1300 329.6247 D 2225394 D Common Stock 2000 I By spouse The sale of shares was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 12, 2026. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $324.49 to $325.34 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $325.50 to $326.4950 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $326.50 to $327.49 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $327.50 to $328.49 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $328.50 to $329.45 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $329.50 to $329.74 per share, inclusive. The holder undertakes to provide, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. /s/ Tami Chen, Attorney-in-Fact 2026-09-11