X0609 4 2026-09-09 0 0000914475 NEUROCRINE BIOSCIENCES INC NBIX 0001643653 BENEVICH ERIC false 6027 EDGEWOOD BEND CT. SAN DIEGO CA 92130 0 1 0 0 Chief Commercial Officer 1 Common Stock 2026-09-09 4 M 0 3194 43.24 A 66562 D Common Stock 2026-09-09 4 S 0 2154 154.61 D 64408 D Incentive Stock Option 43.24 2026-09-09 4 M 0 3194 0 D 2027-02-06 Common Stock 3194 0 D Includes an aggregate of 178 shares purchased on February 27, 2026 and August 31, 2026 from the Neurocrine Biosciences, Inc. 2018 Employee Stock Purchase Plan. The disposition reported in this Form 4 was effected by a broker pursuant to instructions set forth in a Rule 10b5-1 trading plan adopted by the Reporting Person on June 10, 2026. Additionally, Issuer policy restricts the Reporting Person from amending or otherwise modifying any 10b5-1 trading plan subsequent to adoption of the plan. The option was granted February 6, 2017 and vested in 48 equal monthly installments beginning March 6, 2017. These options were due to expire on February 6, 2027. /s/ Darin Lippoldt, Attorney-in-Fact 2026-09-10