X0609 4 2026-08-07 0 0001516551 Skye Bioscience, Inc. SKYE 0001425052 DHILLON PUNIT false 11250 EL CAMINO REAL, SUITE 100 C/O SKYE BIOSCIENCE, INC. SAN DIEGO CA 92130 1 1 0 0 Chief Executive Officer 0 Common Stock 2026-08-07 4 A 0 1090000 0 A 1419823 D Common Stock 9343 I Trust Represents a restricted stock unit ("RSU") award that will vest on August 31, 2027 subject to (a) the Reporting Person's continued employment through such date or (b) the termination of the Reporting Person's employment by the Company for any reason other than For Cause, By Death or By Disability (each, as defined in the Reporting Person's Executive Employment Agreement), provided the Reporting Person executes and does not revoke the release agreement appended to the Reporting Person's Executive Employment Agreement. Each RSU represents a contingent right to receive one share of the Issuer's common stock. Punit Dhillon 2026-08-07