X0609 4 2026-06-24 0 0001655759 ARVINAS, INC. ARVN 0001616284 Saik Andrew false C/O ARVINAS, INC. 5 SCIENCE PARK, 395 WINCHESTER AVE. NEW HAVEN CT 06511 0 1 0 0 Chief Financial Officer 1 Common Stock 2026-06-24 4 S 0 5696 8.159 D 187432 D This sale was made automatically by the Issuer to cover tax withholding obligations in connection with the vesting and settlement of 25% of the reporting person's restricted stock units (RSUs) granted on June 24, 2024, pursuant to a durable sale instruction. The sale does not represent a discretionary trade. /s/ Jared Freedberg, as attorney-in-fact for Andrew Saik 2026-06-24