X0609 4 2026-06-09 0 0002023658 Bicara Therapeutics Inc. BCAX 0001863094 Simson Jake false BICARA THERAPEUTICS INC. 116 HUNTINGTON AVENUE, SUITE 703 BOSTON MA 02116 1 0 0 0 0 Stock Option (Right to Buy) 20.56 2026-06-09 4 A 0 19475 0 A 2036-06-09 Common Stock 19475 19475 D The shares underlying this stock option vest upon the earlier of (i) June 9, 2027 or (ii) the date of the next Annual Meeting of Stockholders of Bicara Therapeutics Inc., subject to the Reporting Person's continued service on such vesting date. Under the Reporting Person's arrangement with RA Capital Management, L.P. (the "Adviser"), the Reporting Person holds the option for the benefit of the R.A. Capital Healthcare Fund, L.P. (the "Fund") and R.A. Capital Nexus Fund III, L.P. (the "Nexus Fund III"). The Reporting Person is obligated to turn over to the Adviser any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund and the Nexus Fund III to the Adviser. The Reporting Person therefore disclaims beneficial ownership of the option and underlying common stock. /s/ Ryan Cohlhepp, Attorney-in-Fact 2026-06-10