X0609 4 2026-06-03 0 0001396814 Pacira BioSciences, Inc. PCRX 0001296965 WILLIAMS KRISTEN false C/O PACIRA BIOSCIENCES, INC. 2000 SIERRA POINT PARKWAY, SUITE 900 BRISBANE CA 94005 0 1 0 0 Chief Administrative Officer 1 Common Stock 2026-06-03 4 F 0 8528 22.32 D 177321 D Common Stock 2026-06-04 4 S 0 10259 22.27 D 167062 D Represents shares withheld by the issuer to cover tax withholding obligations upon vesting of a restricted stock unit award. The sale reported in this Form 4 was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934. The Rule 10b5-1 trading plan was adopted on September 10, 2025. /s/ Kristen Williams 2026-06-05