X0609 4 2026-06-03 0 0001576885 Acumen Pharmaceuticals, Inc. ABOS 0001340881 Drapkin Kimberlee C false C/O ACUMEN PHARMACEUTICALS, INC. 1210-1220 WASHINGTON STREET, SUITE 210 NEWTON MA 02465 1 0 0 0 0 Common Stock 2026-06-03 4 A 0 35500 0 A 48300 D Stock Option (right to buy) 2.29 2026-06-03 4 A 0 53250 0 A 2036-06-03 Common Stock 53250 53250 D Represents a restricted stock unit ("RSU") award. Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. The RSUs will vest in full on the earlier of the first anniversary of the date of grant or the 2027 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. The shares subject to the option will vest in full on the earlier of the first anniversary of the date of grant or the 2027 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date. /s/ Derek Meisner, Attorney-in-Fact 2026-06-05