X0508 4 2026-03-09 0 0001854270 Senti Biosciences, Inc. SNTI 0001816676 Rajangam Kanya C/O SENTI BIOSCIENCES, INC. 2 CORPORATE DRIVE FIRST FLOOR SOUTH SAN FRANCISCO CA 94080 0 1 0 0 Pres. & Chief Med. & Dev. Off. 0 Common Stock 2026-03-09 4 F 0 10757 0 D 74843 D Represents the number of shares of common stock that have been withheld by the Issuer to satisfy its income tax withholding and remittance obligations in connection with the net settlement of certain time-based restricted stock unit awards and does not represent an open market sale. /s/ Robert Cutler, attorney-in-fact 2026-03-09