X0508 4 2026-03-02 0 0001787306 Arcutis Biotherapeutics, Inc. ARQT 0001416180 Leonard Keith R C/O ARCUTIS BIOTHERAPEUTICS, INC. 3027 TOWNSGATE ROAD, SUITE 300 WESTLAKE VILLAGE CA 91361 1 0 0 0 1 Common Stock 2026-03-02 4 M 0 27052 8.63 A 49175 D Common Stock 2026-03-02 4 M 0 12220 7.51 A 61395 D Common Stock 2026-03-02 4 S 0 39272 25.392 D 22123 D Common Stock 1750 I By Leonard Family Trust dated August 28, 1996 Stock Option (right to buy) 8.63 2026-03-02 4 M 0 27052 0 D 2034-06-14 Common Stock 27052 0 D Stock Option (right to buy) 7.51 2026-03-02 4 M 0 12220 0 D 2033-05-31 Common Stock 12220 0 D The transactions reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted on November 18, 2025, by the Reporting Person, with a plan end date of February 16, 2027. The price reported in Column 4 is a weighted average sale price. The shares were sold in multiple transactions at prices ranging from $25.05 to $26.039, inclusive. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. Shares held by Leonard Family Trust dated August 28, 1996, of which the Reporting Person is a trustee. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of such securities for purposes of Section 16 or for any other purposes. The option is fully vested. /s/ Latha Vairavan, as Attorney-in-Fact for Keith Leonard 2026-03-04