X0508 4 2026-02-26 0 0001655759 ARVINAS, INC. ARVN 0001369900 Berkowitz Noah C/O ARVINAS, INC. 5 SCIENCE PARK, 395 WINCHESTER AVE. NEW HAVEN CT 06511 0 1 0 0 Chief Medical Officer 0 Common Stock 2026-02-26 4 A 0 45000 0 A 208938 D Stock Option (right to buy) 13.38 2026-02-26 4 A 0 67000 0 A 2036-02-25 Common Stock 67000 67000 D The restricted stock units (each, an "RSU") were granted by the Issuer on February 26, 2026, pursuant to its 2018 Stock Incentive Plan (the "Plan"), and each RSU represents a contingent right to receive one share of the Issuer's common stock upon settlement for no consideration. The RSUs will vest over four years: one-quarter of the RSUs will vest on each of February 26, 2027, February 26, 2028, February 26, 2029 and February 26, 2030, subject to the Reporting Person's continued service with the Issuer on each such vesting date. The option was granted by the Issuer on February 26, 2026, pursuant to the Plan. The shares underlying the option vest over four years: one-quarter of the shares underlying the award will vest on February 26, 2027, with the remainder of the shares vesting in equal monthly installments following February 26, 2027 through February 26, 2030, subject to the reporting person's continued service with the Issuer on each vesting date. /s/ Jared Freedberg, as attorney-in-fact for Noah Berkowitz 2026-03-02